Results 131 to 140 of about 1,035,590 (321)

Cluster-Driven Expert Pruning for Mixture-of-Experts Large Language Models [PDF]

arXiv
Mixture-of-Experts (MoE) architectures have emerged as a promising paradigm for scaling large language models (LLMs) with sparse activation of task-specific experts. Despite their computational efficiency during inference, the massive overall parameter footprint of MoE models (e.g., GPT-4) introduces critical challenges for practical deployment ...
arxiv  

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

Illustrative Examples of EXPERT SYSTEMS

South African Journal of Industrial Engineering, 2012
<p>ENGLISH ABSTRACT: This paper ",ill attempt to illustrate some of the concepts of expert system technology through the use of simplified examples.</p><p>AFRIKAANSE OPSOMMING: Hierdie artikel poog om sommige van die konsepte van ...
P.S. Kruger
doaj  

What Makes An Expert? Reviewing How ML Researchers Define "Expert" [PDF]

arXiv
Human experts are often engaged in the development of machine learning systems to collect and validate data, consult on algorithm development, and evaluate system performance. At the same time, who counts as an 'expert' and what constitutes 'expertise' is not always explicitly defined.
arxiv  

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

A Methodology Based on Expert Systems for the Early Detection and Prevention of Hypoxemic Clinical Cases. [PDF]

Int J Environ Res Public Health, 2020
Comesaña-Campos A, Casal-Guisande M, Cerqueiro-Pequeño J, Bouza-Rodríguez JB.   +3 more
europepmc   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

EXPERT SYSTEMS IndustriaI Engineering Perspective

South African Journal of Industrial Engineering, 2012
<p>ENGLISH ABSTRACT: The purpose and scope of this paper may be summarized as follows : <br />An attempt to make the Industrial Engineering community aware of the existence and potential benefits of Expert Systems technology, <br /> ...
P.S. Kruger
doaj  

Design and Development of a Methodology Based on Expert Systems, Applied to the Treatment of Pressure Ulcers. [PDF]

Diagnostics (Basel), 2020
Casal-Guisande M, Comesaña-Campos A, Cerqueiro-Pequeño J, Bouza-Rodríguez JB.   +3 more
europepmc   +1 more source

Second Generation Expert Systems

Future Generation Computer Systems, 1985
Second generation expert systems are able to combine heuristic reasoning based on rules, with deep reasoning based on a model of the problem domain. This solves a number of major problems of current expert systems, most importantly the problem of knowledge acquisition: second generation expert systems can learn new rules by examining the results of ...
openaire   +5 more sources