Results 71 to 80 of about 60,361 (257)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Towards Explainability of UAV-Based Convolutional Neural Networks for Object Classification [PDF]

f autonomous systems using trust and trustworthiness is the focus of Autonomy Teaming and TRAjectories for Complex Trusted Operational Reliability (ATTRACTOR), a new NASA Convergent Aeronautical Solutions (CAS) Project.
Allen, Danette, Dolph, Chester V., Tran, Loc D.   +2 more
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

TravelRAG: A Tourist Attraction Retrieval Framework Based on Multi-Layer Knowledge Graph

ISPRS International Journal of Geo-Information
A novel framework called TravelRAG is introduced in this paper, which is built upon a large language model (LLM) and integrates Retrieval-Augmented Generation (RAG) with knowledge graphs to create a retrieval system framework designed for the tourism ...
Sihan Song, Chuncheng Yang, Li Xu, Haibin Shang, Zhuo Li, Yinghui Chang   +5 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Simplified Deep Learning for Accessible Fruit Quality Assessment in Small Agricultural Operations

Applied Sciences
Fruit quality assessment is vital for ensuring consumer satisfaction and marketability in agriculture. This study explores deep learning techniques for assessing fruit quality, focusing on practical deployment in resource-constrained environments.
Víctor Zárate, Danilo Cáceres Hernández   +1 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An Optimization Method for PCB Surface Defect Detection Model Based on Measurement of Defect Characteristics and Backbone Network Feature Information

Sensors
Printed Circuit Boards (PCBs) are essential components in electronic devices, making defect detection crucial. PCB surface defects are diverse, complex, low in feature resolution, and often resemble the background, leading to detection challenges.
Huixiang Liu, Xin Zhao, Qiong Liu, Wenbai Chen   +3 more
doaj   +1 more source

SAFE PERIODS BOTH EXPLAIN AND NEED EXPLAINING [PDF]

Journal of the Experimental Analysis of Behavior, 2001
Dinsmoor's (2001) stress on the response‐produced safe period as a reinforcer for avoidance behavior is a positive contribution, even though several questions about such safe periods remain to be answered.
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source