Results 91 to 100 of about 1,620,962 (292)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sensitivity to Instruction Strategies in Motor Learning Is Predicted by Anterior–Posterior TMS Motor Thresholds

Brain Sciences
Background: The impact of exogenous explicit knowledge on early motor learning is highly variable and may be influenced by excitability within the procedural sensorimotor network.
Michael L. Perrier, Kylee R. Graham, Jessica E. Vander Vaart, W. Richard Staines, Sean K. Meehan   +4 more
doaj   +1 more source

Group explicit methods for the numerical solution of the wave equation

Computers & Mathematics with Applications, 1988
Here the group explicit methods of the authors [ibid. 15(6-8), 659-697 (1988; reviewed above)] and the second author and \textit{A. R. B. Abdullah} [Int. J. Comput. Math. 14, 73-105 (1983; Zbl 0517.65069)] are extended to a first order hyperbolic system.
Sahimi, M.S., Evans, D.J.
openaire   +1 more source

Locally nilpotent derivations on affine surfaces with a $\C^*$-action

, 2004
We give a classification of normal affine surfaces admitting an algebraic group action with an open orbit. In particular an explicit algebraic description of the affine coordinate rings and the defining equations of such varieties is given.
Flenner, Hubert, Zaidenberg, Mikhail
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Alternating Group Explicit Iterative Methods for One-Dimensional Advection-Diffusion Equation

American Journal of Computational Mathematics, 2015
The finite difference method such as alternating group iterative methods is useful in numerical method for evolutionary equations and this is the standard approach taken in this paper. Alternating group explicit (AGE) iterative methods for one-dimensional convection diffusion equations problems are given.
Ning Chen, Haiming Gu
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Differential effects of sleep on explicit and implicit memory for potential trauma reminders: findings from an analogue study

European Journal of Psychotraumatology, 2019
Background: Recent findings suggest that disruptions of sleep-related memory processing are involved in the development of posttraumatic stress symptoms.
M. Roxanne Sopp, Alexandra H. Brueckner, Sarah K. Schäfer, Johanna Lass-Hennemann, Tanja Michael   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Explicit Symplectic Integrators with Adaptive Time Steps in Curved Spacetimes

The Astrophysical Journal Supplement Series
Recently, our group developed explicit symplectic methods for curved spacetimes that are not split into several explicitly integrable parts but are via appropriate time transformations.
Xin Wu, Ying Wang, Wei Sun, Fuyao Liu, Dazhu Ma   +4 more
doaj   +1 more source