Results 121 to 130 of about 1,620,962 (292)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The effect of implicit and explicit motor learning on a targeting task in children with autism spectrum disorder (ASD)

open access: yesActa Psychologica
This study aims to investigate the effect of different implicit and explicit instructions on learning a fundamental motor skill (throwing task) in autistic children with a high propensity for reinvestment.
Morteza Homayounnia Firouzjah   +2 more
doaj   +1 more source

The Effect of Sequential Stimuli Technique on Acquisition, Retention and Transfer of Ocular Motor Sequence [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2010
This research aimed to examine the effect of sequential stimuli technique on acquisition, retention and transfer of ocular motor sequence. First sequential stimuli, time record, response error software was designed.
Kavos Salehi   +3 more
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Desingularizing positive scalar curvature 4-manifolds

open access: yes, 2019
We show that the bordism group of closed 3-manifolds with positive scalar curvature (psc) metrics is trivial by explicit methods. Our constructions are derived from scalar-flat K{\"a}hler ALE surfaces discovered by Lock-Viaclovsky.
Kazaras, Demetre
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The Effect of Explicit and Implicit Instruction on Learning and Retention of Metaphor-based Economic Terms

open access: yesNaqd-i Zabān va Adabīyyāt-i Khārijī, 2017
The purpose of this study was to investigate the effect of explicit and implicit instruction on learning and retention of metaphor-based economic terms on the part of Iranian language learners of Economics.
عادله حیدری   +2 more
doaj  

Trees, homology, and automorphism groups of RAAGs

open access: yes, 2017
We study the homology of an explicit finite-index subgroup of the automorphism group of a partially commutative group, in the case when its defining graph is a tree. More concretely, we give a lower bound on the first Betti number of this subgroup, based
Aramayona, Javier   +3 more
core  

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