Results 101 to 110 of about 2,325,301 (352)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Examining the effectiveness of explicit instruction of vocabulary learning strategies with Japanese EFL university students (pre-print version) [PDF]

open access: yes, 2009
This study examined the effectiveness of explicit instruction of vocabulary learning strategies (VLSs) over a ten-week semester with a group of 146 female EFL learners from two Japanese universities.
Mizumoto Atsushi   +3 more
core   +2 more sources

Getting Explicit Instruction Right

open access: yes
There has been substantial public debate about the potentially deleterious effects of the long-run move to ``inquiry-based learning'' in which students are placed at the center of an educational journey and arrive at their own understanding of what is being taught.
Holden, Richard, Martinenghi, Fabio I.
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

The Effect of Explicit Instruction of Metacognitive Reading Strategies on ESP Reading Comprehension in Academic Settings

open access: yesInternational Journal of Applied Linguistics and English Literature, 2018
This study investigated the effect of explicit instruction of metacognitive reading strategies on ESP reading comprehension among university students in Iran.
P. Ajideh   +2 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Effects of Multimedia Learning Combined With Strategy-Based Instruction on Vocabulary Learning and Strategy Use

open access: yesSAGE Open, 2019
The present study investigated the impact of multimedia-assisted explicit vocabulary learning strategy (VLS) instruction on foreign language learners’ strategy use and vocabulary learning.
Merak Rahimi, Atefeh Allahyari
doaj   +1 more source

The Effect of Explicit, Implicit Instructions and Learning Styles on Students\u27 Sentence Structure Achievement [PDF]

open access: yes, 2011
The objectives of this study are to investigate whether Explicit Instruction and Implicit Instructions techniques significantly affect the students\u27 sentence structure achievement, to find out whether the students\u27 learning styles affect students ...
Debora, M. (Marisi)
core  

The effects of explicit pronunciation instruction on the degree of perceived foreign accent in the speech of EFL learners [PDF]

open access: yes, 2017
This paper reports on a study that attempted to examine the effect of explicit pronunciation instruction of some English segments (individual sounds) on the degree of perceived foreign accent in EFL Arab learners’ speech. Nine Arab learners of English in
Algethami, Ghazi
core   +1 more source

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