Results 51 to 60 of about 267,677 (262)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Explicit and implicit knowledge with regard to the age of learners

open access: yesExELL (Explorations in English Language and Linguistics), 2013
The present study set out to examine learners’ explicit and implicit foreign language knowledge with regard to their age. Therefore, two groups of learners from Zenica and Zavidovići (Bosnia and Herze-govina) presented the pool of informants in this ...
Vildana Dubravac
doaj  

Motor memory consolidation in children: The role of awareness and sleep on offline general and sequence-specific learning

open access: yesBiomedical Human Kinetics, 2022
Study aim: The purpose of this study was to investigate the role of sleep and awareness on consolidation of general and Sequence-Specific learning in children.
Iranmanesh Hamideh   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Implicit Knowledge, Explicit Knowledge, and Achievement in Second Language (L2) Spanish

open access: yesCanadian Journal of Applied Linguistics, 2012
Implicit and explicit knowledge of the second language (L2) are two central constructs in the field of second language acquisition (SLA). In recent years, there has been a renewed interest in obtaining valid and reliable measures of L2 learners ...
Xavier Gutiérrez
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Knowledge in the business strategy context

open access: yesAgricultural Economics (AGRICECON), 2006
The paper builds on the resource-based approach to the firm and develops it further towards the knowledge-based approach by exploring the importance of knowledge in a modern firm.
I. Tichá, J. Hron
doaj   +1 more source

Effects of Tacit Knowledge on the Performance of Selected Universities in Kenya

open access: yesManagement Dynamics in the Knowledge Economy, 2020
Tacit knowledge (TK) is non-codified and personal (sticky) knowledge that is difficult to transfer. TK cannot be said to be significant if there is a lack of tangible contributions. Universities can only realize such returns when there is growth in terms
Murumba Joan Wakasa   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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