Results 91 to 100 of about 140,450 (312)

Astrobiological Field Campaign to a Volcanosedimentary Mars Analogue Methane Producing Subsurface Protected Ecosystem: Imuruk Lake (Alaska)

open access: yesAdvances in Astronomy, 2011
Viking missions reported adverse conditions for life in Mars surface. High hydrogen signal obtained by Mars orbiters has increased the interest in subsurface prospection as putative protected Mars environment with life potential. Permafrost has attracted
F. Gómez   +9 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Mini-rovers for Mars explorations [PDF]

open access: yes
Rovers are desirable for surface exploration because they allow sampling, and sample returns from several diverse locations on a planet's surface. Unfortunately, the rovers currently being examined for Mars exploration have several undesirable features ...
Miller, David P.
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Trade studies for nuclear space power systems [PDF]

open access: yes
As human visions of space applications expand and as we probe further out into the universe, our needs for power will also expand, and missions will evolve which are enabled by nuclear power.
Bents, David J.   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Office of exploration overview [PDF]

open access: yes
The NASA Office of Exploration case studies for FY89 are reviewed with regard to study ground rules and constraints. Three study scenarios are presented: lunar evolution, Mars evolution, and Mars expedition with emphasis on the key mission ...
Alred, John
core   +1 more source

Measuring the Elemental Composition of Phobos: The Mars‐moon Exploration with GAmma rays and NEutrons (MEGANE) Investigation for the Martian Moons eXploration (MMX) Mission

open access: yesEarth and Space Science, 2019
The Mars‐moon Exploration with GAmma rays and NEutrons (MEGANE) investigation will use gamma‐ray and neutron spectroscopy to measure the elemental composition of Mars' moon Phobos.
David J. Lawrence   +15 more
doaj   +1 more source

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