Results 101 to 110 of about 128,266 (357)

Mars [PDF]

open access: yes
This poster of Mars shows a full-disk mosaic, taken by the Mars Global Surveyor. The northern polar ice cap, Tharsis volcanoes, and Valles Marineris are visible.

core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Research on the Detection Method of Martian Atmospheric Temperature and Pressure Profile Based on Laser Occultation Technology

open access: yesRemote Sensing
As an important target of space exploration, Mars has attracted a lot of attention due to its unique geographical and atmospheric conditions. The detection of the vertical profiles of Mars atmospheric parameters provides deeper insights into the ...
Ye Liu   +4 more
doaj   +1 more source

Geology of the Melas Chasma landing site for the Mars Exploration Rover mission [PDF]

open access: bronze, 2003
C. M. Weitz   +4 more
openalex   +1 more source

Participatory Technology Assessment for Mars Mission Planning: Public Values and Rationales [PDF]

open access: yes
Public support and interest are needed to design an ambitious human spaceflight program. However, it is difficult to understand what the public values and would support.
Bertrand, Pierre   +2 more
core   +1 more source

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