Results 91 to 100 of about 490,079 (300)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Knowledge Exploratory for Service Management and Innovation [PDF]

open access: yes, 2008
In this talk, various trends in the current service economy are explained. Global economy has turned out to be a service-oriented economy, in addition to the fact that the economy is going along with more digitized information rather than just labor intensive human service activities.
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Women Entrepreneurship and Innovations in India: An Exploratory Study

open access: yesInternational Journal of Innovation, 2014
Increased female entrepreneurial activity heralds a progress for women’s rights and optimization of their economic and social living index. Women entrepreneurship is synonymous with women empowerment. Parallel to the male counterparts, female entrepreneurs are catalytic in job creation, innovation and more than tangible contribution to the GNP of the ...
Bulsara, Hemantkumar P.   +2 more
openaire   +2 more sources

Regional food clusters and government support for clustering: Evidence for a ‘dynamic food innovation cluster’ in Alberta, Canada? [PDF]

open access: yes
Location-based clusters and virtual cluster configurations have received significant attention from policymakers due to their potential implications on productivity, innovation and regional growth.
Ali, Jolene, Steiner, Bodo
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The evolution of the ambidextrous innovation synergy strategy of new entrants from the perspective of key core technology monopoly

open access: yesHeliyon
Ambidextrous innovation synergy is an effective way for new entrants and R&D entities to break the blockade of key core technologies. This paper constructs a tripartite evolutionary game model of new entrants, the R&D entity, and monopoly enterprises ...
Shuang Yao, Leke Wu, Donghua Yu
doaj   +1 more source

Cell culture conditions affect the ability of high content imaging assay to detect drug-induced changes in cellular parameters in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)

open access: yesToxicology Reports, 2019
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are widely used for drug safety and efficacy testing with various techniques, including high content imaging (HCI).
Bharathi Balasubramanian   +5 more
doaj   +1 more source

PORTFOLIO MANAGEMENT OF INNOVATION FIELDS : APPLYING CK DESIGN THEORY IN CROSS INDUSTRY EXPLORATORY PARTNERSHIP [PDF]

open access: yes
Our paper refers to an industrial practice based on an integrated theoretical framework of design, CK design theory (Hatchuel and Weil, 2002, Hatchuel and Weil, 2003, Hatchuel and Weil, 2008), to support people in management of innovation fields.
Benoît Roussel   +3 more
core  

Collaborative Mapping of London Using Google Maps: The LondonProfiler [PDF]

open access: yes, 2008
This paper begins by reviewing the ways in which the innovation of Google Maps has transformed our ability to reference and view geographically referenced data.
Gibin, M   +4 more
core  

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