Results 41 to 50 of about 2,505,841 (292)

Business Model Innovation in Airlines [PDF]

open access: yes, 2017
The business models innovation in airlines can contribute to the creation of value, competitive advantage and profitability with new possibilities of action.
Mauro Caetano   +3 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Encouraging innovation activity: in the specific context of small- and medium-sized retailers [PDF]

open access: yes, 2015
This paper aims at formalizing an innovation process well suited for small- and medium-sized enterprises (SMEs) specialized in retail. The design research consisted in analyzing conceptual models of innovation process from the literature and adapting it ...
BUISINE, Stéphanie   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Concept and Process of Innovation Leading Based on the longitudinal case study of Haier (1984-2019) [PDF]

open access: yesE3S Web of Conferences, 2020
Based on the exploratory case study method, this paper attempts to construct a theoretical framework of Innovation Leading from two aspects of concept and process. Based on this research framework, the article makes a longitudinal case study of the Haier
Yuyue Kan, Haibing Liu
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Research on the impact of data factor marketization on organizational resilience of resource-based enterprises: a moderated mediation model

open access: yesFrontiers in Communication
IntroductionThis study examines the impact of data element marketization on the organizational resilience of resource-based firms. Drawing on dynamic capability theory and ambidextrous innovation theory, it analyzes the chain mediation effect of ...
Fengzheng Wang   +3 more
doaj   +1 more source

Brite innovation survey : executive summary [PDF]

open access: yes, 2005
This report summarises the fi ndings of an innovation survey\ud of the Australian construction industry undertaken by the\ud BRITE Project of the CRC for Construction Innovation in\ud 2004.

core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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