Results 61 to 70 of about 490,079 (300)
Exploratory Innovation, Exploitative Innovation, and Ambidexterity: The Impact of Environmental and Organizational Antecedents [PDF]
Schmalenbach Business Review, 2005 Organizational ambidexterity (i.e., the ability to pursue exploratory and exploitative innovation simultaneously) is crucial to firm survival. In this study we explore how multiunit firms might develop ambidextrous organizational units in response to environmental demands.
Jansen, Justin +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Frontiers in Human DynamicsIntroductionEmployees play a pivotal role in organizational ambidextrous innovation, yet existing studies have paid limited attention to how artificial intelligence shapes employees’ exploitative and exploratory innovation. Drawing on cognitive appraisal
Li Liu, Ya Lv
doaj +1 more source
Investigating co-innovation in exploratory partnerships: An analytical framework based on design theory [PDF]
, 2008 International audienceIntensive innovation contexts push organizations to search for new partnerships in order to explore value creation opportunities and to access external resources.
Gillier, Thomas +2 more
core +1 more source
Small businesses in the new creative industries:innovation as a people management challenge [PDF]
, 2011 Purpose - This paper presents findings from an SME case study situated in the computer games industry, the youngest and fastest growing of the new digital industries.
Champion, Katherine, Hotho, Sabine
core +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Perceived value of microfinance and SME performance: The role of exploratory innovation
International Journal of Innovation StudiesThis study examines how perceived value of microfinance and exploratory innovation affect small and medium-sized enterprises (SME) performance in the context of a developing nation.
Christian Sarfo +3 more
doaj +1 more source
Unbundling dynamic capabilities: an exploratory study of continuous product innovation [PDF]
Industrial and Corporate Change, 2003 In order to understand better the organizational sources of continuous innovation, this paper provides an in‐depth analysis of Oticon A/S, a leading company in the hearing‐aid industry, which showed an impressive ability to develop new products in the nineties.
VERONA, GIANMARIO, RAVASI, DAVIDE
openaire +3 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source