Results 51 to 60 of about 490,079 (300)

Fueling exploitative and exploratory innovation with paternalistic leadership – do intrinsic motivation and environmental dynamism moderate the relationship? [PDF]

Management Science Letters
The objectives of the study were to investigate 1) whether paternalistic leadership affects exploitative and exploratory innovation, and 2) whether intrinsic motivation and environmental dynamism moderate the direct effects of paternalistic ...
vedha De Costa, Vathsala Wickramasinghe
doaj   +1 more source

Research on dual innovation incentive mechanism in terms of organizations' differential knowledge absorptive capacity.

PLoS ONE, 2021
Differences in the capacity for absorption between different organizations will have an important impact on an organization's choices of innovation exploration and exploitive innovation strategies.
Xuejiao An, Lin Qi, Jian Zhang, Xinran Jiang   +3 more
doaj   +1 more source

Academic Community Perceptions of Open Innovation: An Exploratory Study

, 2023
This study seeks to assess the academic community’s knowledge and perception of open innovation. While the so-called “closed innovation” is rooted in the discourse of future managers, open innovation, being a relatively recent paradigm, may be an unknown form of innovation and therefore its potential is underused.
Tiago Rodrigues-Sa, Manuel Au-Yong-Oliveira   +1 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Research on the Impact and Path of Human-Machine Collaborative Decision-Making on Dualistic Innovations

IEEE Access
Intelligent and virtualized transformation of the enterprise requires employees to undertake both technological breakthroughs and in-depth development, two innovative activities that seem to compete for resources. How employees, guided by algorithmically
Bin Miao, Jiage Zhang, Jiaxing Zhang, Lu Li, Yitong Hou   +4 more
doaj   +1 more source

Swimming for dementia: An exploratory qualitative study: Innovative practice [PDF]

Dementia, 2018
Swimming is a non-weight bearing form of exercise that can be enjoyable and promote physical fitness. This qualitative study investigated a local group established as part of a national dementia swimming initiative. Semi-structured interviews with people with dementia (N = 4), carers or companions (N = 4) and the organisers and facilitators of the ...
Tanya, Hobden, Mary, Swallow, Charlotte, Beer, Tom, Dening   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Winning by Intelligence: Leveraging the Innovative Advantages of Intelligent Transformation in Market Competition

Systems
Intelligent transformation plays an important role in enhancing innovation capabilities. This study utilizes data from 5000 A-share firms in China to investigate the effects of intelligent transformation on innovation capability and to elucidate the ...
Jingwen Lv, Lu Feng, Wei Xiao, Wei He
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source