Results 41 to 50 of about 469,234 (267)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Multi-Cycle Deliverability Analysis of Underground Gas Storage Considering Stress Sensitivity

Energies
The cyclic injection production operations in underground gas storage (UGS) facilities lead to alternating changes in effective stress, resulting in irreversible permeability damage and productivity decline.
Kuanguo Li, Xiaofan Chen, Yu Mu, Yifan Zou, Yun Zhang   +4 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Las Instituciones del Endeudamiento Municipal en México: un Enfoque de Teoría de Juegos

Sobre México, 2015
El proceso democratizador experimentado en México en los últimos veinte años trajo consigo la promesa de gobiernos más cercanos a los ciudadanos, que respondieran de mejor forma a sus demandas, y sobre todo que ofrecieran mejores soluciones a los ...
Eduardo Sierra Albarrán, Junior Alfredo Martínez   +1 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Interaction of the Mechano-Electrical Feedback With Passive Mechanical Models on a 3D Rat Left Ventricle: A Computational Study

Frontiers in Physiology, 2019
In this paper, we are investigating the interaction between different passive material models and the mechano-electrical feedback (MEF) in cardiac modeling.
Minh Tuấn Du'o'ng, Minh Tuấn Du'o'ng, David Holz, Muhannad Alkassar, Sven Dittrich, Sigrid Leyendecker   +5 more
doaj   +1 more source

Heat transfer effects on flow past an exponentially accelerated vertical plate with variable temperature [PDF]

Theoretical and Applied Mechanics, 2008
An exact solution to the problem of flow past an exponentially accelerated infinite vertical plate with variable temperature is analyzed. The temperature of the plate is raised linearly with time t.
Muthucumaraswamy R., Sathappan K.E., Natarajan R.   +2 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mathematical Modeling and Analysis of Tumor Growth Models Integrating Treatment Therapy

Mathematical and Computational Applications
This study presents a comparative analysis of tumor growth models based on logistic, exponential, and Gompertz formulations. Their response to therapeutic intervention is examined to identify which model shows better behavior with minimal decline of ...
Mohsin Kamran, Johari Yap Abdullah, Afaf Syahira Ahmad Satmi, Maya Genisa, Abdul Majeed, Tayyaba Nadeem   +5 more
doaj   +1 more source