Results 41 to 50 of about 102,666 (260)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
On the Distribution of the Product of Inverse Pareto and Exponential Random Variables
Recoletos Multidisciplinary Research Journal, 2023 This article considers Inverse Pareto and Exponential distributions to create the distribution of the product. The researchers derived its properties, such as; survival functions and hazard functions, and used the model criterion such as Sum Square Error
Marvin Pizon
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Bounds for a spectral exponential sum [PDF]
Journal of the London Mathematical Society, 2018 We prove new upper bounds for a spectral exponential sum by refining the process by which one evaluates mean values of $L$-functions multiplied by an oscillating function. In particular, we introduce a method which is capable of taking into consideration the oscillatory behaviour of the function.
Olga Balkanova, Dmitry Frolenkov
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
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Reconsideration of sample size and power calculation for overall survival in cancer clinical trials
Contemporary Clinical Trials Communications, 2018 When designing a cancer clinical trial, it is usual to assume an exponential distribution for a time-to-event outcome such as overall survival (OS). OS is often expressed as the sum of progression-free survival (PFS) and survival post-progression (SPP ...
Inkyung Jung +3 more
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Asymptotic results for a class of Markovian self-exciting processes
Journal of Inequalities and Applications, 2023 Hawkes process is a class of self-exciting point processes with clustering effect whose jump rate relies on their entire past history. This process is usually defined as a continuous-time setting and has been widely applied in several fields, including ...
Youngsoo Seol
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Finite Fields and Their Applications, 1995 This paper along with \textit{J. Angel} [Finite Fields Appl. 2, 62-86 (1996; see the preceding review)] and \textit{R. Evans} [Finite Fields Appl. 1, 376-394 (1995; Zbl 0844.11078)] proves that finite upper half plane graphs are Ramanujan in characteristic 2. Ramanujan graphs were first defined by \textit{A. Lubotzky}, \textit{R.
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source