Results 51 to 60 of about 786,873 (284)
Reconsideration of sample size and power calculation for overall survival in cancer clinical trials
Contemporary Clinical Trials Communications, 2018 When designing a cancer clinical trial, it is usual to assume an exponential distribution for a time-to-event outcome such as overall survival (OS). OS is often expressed as the sum of progression-free survival (PFS) and survival post-progression (SPP ...
Inkyung Jung +3 more
doaj +1 more source
A Closed-Form Solution to the Arbitrary Order Cauchy Problem with Propagators [PDF]
, 2014 The general abstract arbitrary order (N) Cauchy problem was solved in a closed form as a sum of exponential propagator functions. The infinite sparse exponential series was solved with the aid of a homogeneous differential equation. It generated a linear
Stenlund, Henrik
core
The Weight Distributions of a Class of Cyclic Codes with Three Nonzeros over F3
, 2013 Cyclic codes have efficient encoding and decoding algorithms. The decoding error probability and the undetected error probability are usually bounded by or given from the weight distributions of the codes.
Liu, Xiaogang, Luo, Yuan
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Note on Cube-Full Numbers in Arithmetic Progression
Journal of Mathematics, 2021 We obtain an asymptotic formula for the cube-full numbers in an arithmetic progression n≡lmod q, where q,l=1. By extending the construction derived from Dirichlet’s hyperbola method and relying on Kloosterman-type exponential sum method, we improve the ...
Mingxuan Zhong, Yuankui Ma
doaj +1 more source
Odd Exponential-Logarithmic Family of Distributions: Features and Modeling
Mathematical and Computational Applications, 2022 This paper introduces a general family of continuous distributions, based on the exponential-logarithmic distribution and the odd transformation. It is called the “odd exponential logarithmic family”.
Christophe Chesneau +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Bounds for a spectral exponential sum [PDF]
Journal of the London Mathematical Society, 2018 We prove new upper bounds for a spectral exponential sum by refining the process by which one evaluates mean values of $L$-functions multiplied by an oscillating function. In particular, we introduce a method which is capable of taking into consideration the oscillatory behaviour of the function.
Olga Balkanova, Dmitry Frolenkov
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source