Results 91 to 100 of about 1,483,300 (312)

Positive exponential sums and odd polynomials [PDF]

open access: yes, 2013
Given an odd integer polynomial f(x) of a degree k >=3, we construct a non-negative valued, normed trigonometric polynomial with the spectrum in the set of integer values of f(x) not greater than n, and a small free coefficient a_{0}=O((\log n)^{-1/k ...
Nincevic, Marina, Slijepcevic, Sinisa
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Hybrid Power Mean of Sixth Gauss Sums and the Two-Term Exponential Sums

open access: yesJournal of Applied Mathematics
The principal aim of this paper is to analyze the hybrid power mean value of sixth Gauss sums and two-term exponential sums. It will use various analytic methods and elementary methods to develop unique identities for these types of sums.
Xuan Wang
doaj   +1 more source

The fourth power mean of the three–term exponential sums

open access: yesElectronic Research Archive
By employing trigonometric sums and solving congruence equations, this paper explores the power mean of a specific class of high–order three–term exponential sums, and derives intriguing identities in the process.
Xiaoge Liu, Guohui Chen
doaj   +1 more source

Randomly stopped sums with exponential-type distributions

open access: yesNonlinear Analysis, 2017
Assume that {ξ1, ξ2, …} are independent and possibly nonidentically distributed random variables. Suppose that η is a nonnegative, nondegenerate at zero and integer-valued random variable, which is independent of {ξ1, ξ2, …}.
Svetlana Danilenko   +2 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

On the Sixth Power Mean Value of the Generalized Three-Term Exponential Sums

open access: yesAbstract and Applied Analysis, 2014
The main purpose of this paper is using the estimate for trigonometric sums and the properties of the congruence equations to study the computational problem of one kind sixth power mean value of the generalized three-term exponential sums and give an ...
Yahui Yu, Wenpeng Zhang
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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