Results 211 to 220 of about 3,657 (262)

Ignoring the planet: A critical blind spot for research on ageing. [PDF]

open access: yesJ Intern Med
Shiels P   +6 more
europepmc   +1 more source

A review of the applications and challenges of applying partial least squares (PLS) to exposomics research

Analytica Chimica Acta
BACKGROUND Partial Least Squares (PLS) regression is a valuable tool in Environmental Health for elucidating the intricate relationships between external environmental exposures and internal biological responses linked to health outcomes in both ...
Beatriz Galindo-Prieto, Ian S Mudway
exaly   +2 more sources

Blood Sample Preparation for Human Chemical Exposomics: Insights from Large-Scale Applications

Environmental Science & Technology
Liquid chromatography-high-resolution mass spectrometry (LC-HRMS) enables profiling of hundreds of externally derived chemicals and their metabolites in human biofluids to capture the internal chemical exposome.
Jade Chaker   +2 more
exaly   +2 more sources

The Exposome and Asthma

Clinics in Chest Medicine, 2019
This article on exposome and asthma focuses on the interaction of patients and their environments in various parts of their growth, development, and stages of life. Indoor and outdoor environments play a role in pathogenesis via levels and duration of exposure, with genetic susceptibility as a crucial factor that alters the initiation and trajectory of
Ahila, Subramanian, Sumita B, Khatri
openaire   +2 more sources

The exposome in rheumatoid arthritis

Joint Bone Spine, 2022
The exposome integrates the variety and accumulation of exposures (external and internal) to which an individual is submitted to from conception to death. Exposome may therefore be a useful tool for understanding the diversity of these factors and their role in the pathophysiology of rheumatoid arthritis (RA).
Jerome, Biton   +5 more
openaire   +2 more sources

A focus on the neural exposome

Neuron, 2022
Many neurological disorders have complex etiologies that include noninheritable factors, collectively called the neural exposome. The National Institute of Neurological Disorders and Stroke is developing a new office with goals to advance our understanding of the multiple causes of neurological illness and to enable the development of more effective ...
Amir P, Tamiz   +3 more
openaire   +2 more sources

The Exposome and Cardiovascular Health

Canadian Journal of Cardiology, 2023
The study of the interplay between social factors, environmental hazards, and health has garnered much attention in recent years. The term "exposome" was coined to describe the total impact of environmental exposures on an individual's health and well-being, serving as a complementary concept to the genome.
Issam Motairek   +3 more
openaire   +2 more sources

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