Results 221 to 230 of about 3,657 (262)

Advancing Exposomics: From Concept to Practice in Environmental Health Sciences.

Environmental Health Perspectives
BACKGROUND Exposomics is a conceptual framework positioned at the intersection of environmental health sciences and precision medicine. It seeks to comprehensively understand how environmental exposures and the body's response to these exposures impact ...
Alison A Motsinger-Reif, D. Balshaw, L. Birnbaum, Yuxia Cui, Curt T. DellaValle, Cinnamon A Dixon, Erin Iturriaga, D. Jett, A. Miller, Victoria K Shanmugam, S. Temkin, R. Kwok   +11 more
semanticscholar   +1 more source

An Exposomics Analysis of 125 Biomarkers of Exposure to Food Contaminants and Biomarkers of Oxidative Stress: A Randomized Cross-Over Chrononutrition Trial of Healthy Adults

Environment International
Background Contaminants in food counteract the beneficial effects of nutrients by interfering with their absorption/distribution/metabolism/excretion characteristics and implicated in chronic disease pathogenesis. The CIRCA CHEM chrononutrition trial was
Hayley Kunde, E. Ioannou, Jasmin Chovatiya, Ravikumar Jagani, P. Charisiadis, Manish Arora, Syam S. Andra, Konstantinos C. Makris   +7 more
semanticscholar   +1 more source

Environmental Exposures and Health Risks: A Metabolomics Perspective on Exposomics Research.

Annual Review of Analytical Chemistry
Exposomics refers to the comprehensive analysis of environmental exposures over the lifespan and assessment of their biological effects on human health.
Ana Ruxandra Stanciu, Clare Gillespie, P. Britz‐McKibbin   +2 more
semanticscholar   +1 more source

Exposomics: The Exposome in Early Life

2019
Individuals are exposed to a wide range of environmental factors of different nature, social, physical, and chemical over their lifetime. The cumulative effect of these environmental stressors, their interaction with genetic factors and key susceptible developmental stages determines disease risks.
Léa Maitre, Martine Vrijheid
openaire   +1 more source

Association between insecticide exposomics and cognitive function in older adults: an observational study based on NHANES 2011–2014

Frontiers in Public Health
Objective This study aims to investigate the association between exposure to insecticide exposomics and cognitive function, among adults aged 60 and above.
Mengfan Zhang, Xiaofang Guo, Yuan Chen, Xinghua Liu, Xingdong Lin   +4 more
semanticscholar   +1 more source

Dried blood spots analysis for targeted and non-targeted exposomics

medRxiv
Dried blood spots (DBS) are an established sample type, widely used in newborn screening programs for monitoring metabolic diseases. Their minimally invasive nature offers great promise for assessing chemical exposures, particularly during early life ...
V. Hernandes, Maximilian Zeyda, L. Wisgrill, B. Warth   +3 more
semanticscholar   +1 more source

The Exposome and Human Health

Environmental Science & Technology
Peer ...
Pablo Gago-Ferrero, Ian Cousins, Akhgar Ghassabian, Marja Lamoree, Daniel Schlenk, Leisa-Maree Toms, Bin Wang, Julie Zimmerman   +7 more
openaire   +5 more sources

The Exposome in Toxicologic Pathology

Toxicologic Pathology, 2020
The “exposome” is an individual’s lifetime spectrum of chemical exposures beginning at conception. An exposome includes general external influences such as pollution and weather; external individual-specific factors (diet, infections, self-selected chemical intake); and internal individual-specific constituents (metabolic byproducts, microbiome ...
Brad Bolon, Wanda M. Haschek
openaire   +2 more sources

Cumulative Impacts: Scientific Drivers and Approaches from Exposomics and Sustainability

Environmental Justice
The Environmental Protection Agency’s Interim Framework for Advancing Consideration of Cumulative Impacts was issued as a foundation for implementing approaches to address the cumulative burden of environmental exposures and health disparities that ...
Andrew M. Geller
semanticscholar   +1 more source

Advancements in Assays for Micro- and Nanoplastic Detection: Paving the Way for Biomonitoring and Exposomics Studies.

Annual Review of Pharmacology and Toxicology
Although plastic pollution and exposure to plastic-related compounds have received worldwide attention, health risks associated with micro- and nanoplastics (MNPs) are largely unknown.
Kuanliang Shao, Runyu Zou, Zhuo Zhang, L. Mandemaker, Sarah Timbie, Ron Smith, Amanda M Durkin, Hanna M. Dusza, Florian Meirer, Bert M Weckhuysen, T. Alderete, Roel Vermuelen, Douglas I Walker   +12 more
semanticscholar   +1 more source