Results 111 to 120 of about 7,091,564 (299)

exposure assessment

Citation: 'exposure assessment' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14673 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Arctic Monitoring and Assessment Programme Assessment 2013: Arctic Ocean Acidification

, 2013
Report documenting the findings and recommendations of the first comprehensive assessment of Arctic Ocean acidification (AOA) conducted by the Arctic Monitoring and Assessment Programme (AMAP).
Arctic Monitoring and Assessment Programme
core  

A Meta-analysis of Asbestos and Lung Cancer: Is Better Quality Exposure Assessment Associated with Steeper Slopes of the Exposure-Response Relationships? [PDF]

, 2011
Background: Asbestos is a well-recognized cause of lung cancer, but there is considerable between-study heterogeneity in the slope of the exposure-response relationship.Objective: We considered the role of quality of the exposure assessment to ...
Heederik, D., Lützen Portengen, Lenters, V.C., Dep IRAS, Roel Vermeulen, Portengen, L., Risk Assessment of Toxic and Immunomodulatory Agents, Leslie Stayner, Lenters, V, Dick Heederik, Burdorf, Lex; id_orcid, Stayner, L., Vermeulen, R., Virissa Lenters, Stayner, L, Burdorf, Lex, Dogger, S., Burdorf, A., Sies Dogger, Alex Burdorf, Heederik, D, Vermeulen, R, Dogger, S, Portengen, L   +23 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Modification of associations between ambient PM2.5 and vital signs by β-blocker prescription status among individuals with heart failure

Environmental Health
Background Fine particulate matter (PM2.5) is associated with cardiovascular morbidity, especially among individuals with pre-existing cardiovascular conditions, such as heart failure (HF).
Morgan Narain, Miyuki Breen, Alex P. Carll, Mehdi Hazari, Aimen Farraj, Cavin K. Ward-Caviness   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cocktail effects of clothianidin and imidacloprid in zebrafish embryonic development, with high and low concentrations of mixtures

Frontiers in Toxicology
There is growing concern that sprayed neonicotinoid pesticides (neonics) persist in mixed forms in the environmental soil and water systems, and these concerns stem from reports of increase in both the detection frequency and concentration of these ...
Seonggeun Zee, Seonggeun Zee, Seonggeun Zee, Moonjung Hyun, Hee-Jung Sim, Kanghee Kim, Ju-Chan Kang, Chang-Beom Park   +7 more
doaj   +1 more source