Results 91 to 100 of about 900,292 (307)

Antimicrobial activity of biogenically produced spherical Se-nanomaterials embedded in organic material against Pseudomonas aeruginosa and Staphylococcus aureus strains on hydroxyapatite-coated surfaces [PDF]

, 2017
In an effort to prevent the formation of pathogenic biofilms on hydroxyapatite (HA)-based clinical devices and surfaces, we present a study evaluating the antimicrobial efficacy of Spherical biogenic Se-Nanostructures Embedded in Organic material (Bio Se-
Demeter M., Lampis S., Lemire J. A., Piacenza E., Presentato A., Turner R. J., Vallini G., Zonaro E.   +7 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Review on standardized assessment and monitoring of the biosafety and biosecurity in laboratories

One Health & Risk Management, 2023
Introduction. Biological risks continue to intensify due to globalization and the ongoing emergence and re-emergence of communicable diseases. These factors are among the primary destabilizing elements of biological security and remain a major concern ...
Irina LOZNEANU
doaj  

Optimization of the bi-oleothermal treatment process for wood preservation and fireproofing [PDF]

, 2011
The bi-oleothermal© process (combination of oil and heat treatment) is a well mastered alternative method for wood protection. However, the fire behavior and resistance to decay of bi-oleothermally treated wood are not good enough to ensure performance ...
Alfos, Carine, Céron, Mathieu, Goyer, Morgan, Kutnik, Magdalena, Simon, Frédéric, Thévenon, Marie-France   +5 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Healthy and sustainable spaces, biosafety and wastes [PDF]

Revista Brasileira em Promoção da Saúde, 2011
Objective: To address the factors needed to develop an action plan towards building healthy public policy within the housing. Data Synthesis: As applied method, we combine concept and practice of healthy housing and other related concepts such as ...
Simone Cynamon Cohen, Débora Cynamon Kligerman, Mara Rejane Barroso Barcelos   +2 more
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]

, 2017
INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K., Mantravadi, Santhi, Ogdie, Alexis   +2 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Medidas de biossegurança em audiologia Biosafety precautions in audiology

Revista CEFAC, 2008
TEMA: Biossegurança na atuação audiológica. OBJETIVO: rever as medidas de precaução-padrão na literatura para o controle de infecção na audiologia.
Patrícia Cotta Mancini, Letícia Caldas Teixeira, Luciana Macedo de Resende, Adriana Martins Gomes, Laélia Cristina Caseiro Vicente, Patrícia Marques de Oliveira   +5 more
doaj   +1 more source