Results 51 to 60 of about 900,292 (307)
Identification of early gene expression changes in primary cultured neurons treated with topoisomerase I poisons. [PDF]
, 2016 Topoisomerase 1 (TOP1) poisons like camptothecin (CPT) are currently used in cancer chemotherapy but these compounds can have damaging, off-target effects on neurons leading to cognitive, sensory and motor deficits.
Butchbach, Matthew E.R. +7 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Epidemiologia e Serviços de SaúdeOBJETIVO: descrever as características dos acidentes de trabalho com material biológico atendidos em um hospital público do estado do Paraná, Brasil, no ano de 2012.
Geanna Mendonça Giancotti +4 more
doaj +1 more source
Tuberculosis in hospital environment: clinical profile in a tertiary hospital from Ceará and level of knowledge of health personnel about control measures [PDF]
Revista Brasileira em Promoção da Saúde, 2010 Objectives: To describe clinical and epidemiological characteristics of inpatients with tuberculosis (TB) and to assess the knowledge of health personnel on fundamental concepts about TB and control measures for pulmonary tuberculosis in a hospital ...
Roberto da Justa Pires Neto +7 more
doaj
Clinics, 2009 INTRODUCTION: S. aureus is one of the main agents of nosocomial infection and is sometimes difficult to treat with currently available active antimicrobials.
Milton Jorge de Carvalho +7 more
doaj +1 more source
Non-lethal effects of entomopathogenic nematode infection
Scientific Reports, 2021 Entomopathogenic nematodes are typically considered lethal parasites of insect hosts. Indeed they are employed as such for biological control of insect pests.
Camila C. Filgueiras, Denis S. Willett
doaj +1 more source
Casting a wide net: use of diverse model organisms to advance toxicology [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Hahn, M. E., & Sadler, K. C. Casting a wide net: use of diverse model organisms to advance toxicology.
Hahn, Mark E., Sadler, Kirsten C.
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Bacillus anthracis como ameaça terrorista
Saúde em DebateApós 2001, a utilização de patógenos reforçou seu emprego como arma de guerra. Este estudo descritivo tem por objetivo discutir estratégias de contingenciamento em ataque por anthrax, auxiliando no reconhecimento precoce e estabelecimento de medidas de ...
Telma Abdalla de Oliveira Cardoso +1 more
doaj +1 more source
Biosafety and Biohazards: Understanding Biosafety Levels and Meeting Safety Requirements of a Biobank. [PDF]
, 2019 When it comes to biobanking and working with different types of laboratory specimens, it is important to understand potential biohazards to ensure safety of the operator and laboratory personnel.
Gosa, Laura +2 more
core +2 more sources