Results 11 to 20 of about 5,546,459 (287)
GC content of vertebrate exome landscapes reveal areas of accelerated protein evolution
BMC Evolutionary Biology, 2019 Background Rapid accumulation of vertebrate genome sequences render comparative genomics a powerful approach to study macro-evolutionary events. The assessment of phylogenic relationships between species routinely depends on the analysis of sequence ...
R. Huttener +6 more
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Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function
Nature Communications, 2020 ATRX is an RNA binding protein that mediates targeting of polycomb repressive complex 2 (PRC2) to genomic sites. Here the authors identify the RNA binding region and show that the RNA binding is required for ATRX localization and for its recruitment of ...
Wenqing Ren +11 more
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Journal of New Approaches in Educational Research, 2018 El objetivo de este trabajo es desarrollar una escala para conocer la percepción de los docentes de Educación Primaria y Secundaria del modelo de currículo basado en competencias en España.
Luis Miguel García-López +3 more
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Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling
Nature Communications, 2021 Long-range looping of an enhancer to a promoter (E-P looping) is a key feature of gene activation; thus, regulation of E-P looping could serve as an effective strategy to precisely control gene expression.
Dahong Chen +4 more
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Establishment of human iPSC-based models for the study and targeting of glioma initiating cells
Nature Communications, 2016 Glioma can originate from the transformation of neural progenitor cells into glioma initiating cells. Here, the authors demonstrate the use of induced pluripotent stem cells as a suitable model for generating neural progenitor cells, which can be ...
Ignacio Sancho-Martinez +22 more
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BMC Genomics, 2017 Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov +2 more
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Sequencing refractory regions in bird genomes are hotspots for accelerated protein evolution
BMC Ecology and Evolution, 2021 Background Approximately 1000 protein encoding genes common for vertebrates are still unannotated in avian genomes. Are these genes evolutionary lost or are they not yet found for technical reasons?
R. Huttener +11 more
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Genome‐wide allele‐ and strand‐specific expression profiling
Molecular Systems Biology, 2009 Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...
Julien Gagneur +5 more
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Motivational Assessment of Engineering Students at two centres of the University of Extremadura
Advances in Building Education, 2022 The student's motivational orientation is an indispensable factor for adequate learning during their formative years. The knowledge of motivational orientations allows teachers to enhance the performance of their students.
Jaime González-Domínguez +5 more
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BMC Research Notes, 2022 Objectives The objective of this data set was to identify how interaction between temperature and the sickle-3 (sic-3) mutant alters the global messenger RNA (mRNA) content of Arabidopsis thaliana seedlings.
Carine M. Marshall, Frank G. Harmon
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