Results 21 to 30 of about 8,188,103 (287)

Calcium sensing by the STIM1 ER-luminal domain

Nature Communications, 2018
Stromal interaction molecule 1 (STIM1) monitors ER-luminal Ca2 + levels to maintain cellular Ca2 + balance. Here the authors find that the STIM1 luminal domain monomer has multiple Ca2 + - binding sites which set the threshold for physiological ...
Aparna Gudlur, Ana Eliza Zeraik, Nupura Hirve, V. Rajanikanth, Andrey A. Bobkov, Guolin Ma, Sisi Zheng, Youjun Wang, Yubin Zhou, Elizabeth A. Komives, Patrick G. Hogan   +10 more
doaj   +1 more source

Gene Co-expression Network and Copy Number Variation Analyses Identify Transcription Factors Associated With Multiple Myeloma Progression [PDF]

, 2019
Multiple myeloma (MM) has two clinical precursor stages of disease: monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). However, the mechanism of progression is not well understood.
Abu Zaid, Mohammad, Han, Zhi, Huang, Kun, Huang, Zhi, Johnson, Travis S., Xiang, Shunian, Yu, Christina Y., Zhan, Xiaohui   +7 more
core   +5 more sources

Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction As new late‐onset Alzheimer's disease (LOAD) genetic risk loci are identified and brain cell–type specific omics data becomes available, there is an unmet need for a bioinformatics framework to prioritize genes and variants for testing in ...
Michael W. Lutz, Ornit Chiba‐Falek
doaj   +1 more source

A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression [PDF]

, 2019
Background: Psoroptic mange, caused by infestation with the ectoparasitic mite, Psoroptes ovis, is highly contagious, resulting in intense pruritus and represents a major welfare and economic concern for the livestock industry Worldwide.
Bartley, Kathryn, Burgess, Stewart TG, Down, Rachel E, Dunn, Jackie, Marr, Edward J, Nisbet, Alasdair J, Nunn, Francesca G, Prickett, Jessica C, Rombauts, Stephane, Van de Peer, Yves, Van Leeuwen, Thomas, Weaver, Robert J   +11 more
core   +2 more sources

Identification and Expression Analysis of Zinc Finger A20/AN1 Stress-Associated Genes SmSAP Responding to Abiotic Stress in Eggplant

Horticulturae, 2022
Stress-associated proteins (SAP), a class of zinc-finger proteins, have been identified as novel stress regulatory proteins in stress responses. However, SAP genes in eggplant (SmSAP) have been little reported.
Faxiang Wan, Yuhu Xu, Sulong Wang, Jun Gao, Dan Lu, Chenghong Zhou, Yanqing Liao, Yanyan Ma, Yu Zheng   +8 more
doaj   +1 more source

The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer. [PDF]

, 2012
Summary In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical analysis was possible in 91.5% of the patients (75/82). Staining was evaluated using
Berger U, Berger U, Boecker W, Conde I, Eisman JA, Frampton RJ, Freake HC, Gombart AF, Jeschke U, Mason BH, Mylonas I, Remmele W, Ulmann A, Zinser GM   +13 more
core   +2 more sources

Genome-Wide Identification of Sucrose Transporter Genes and Functional Analysis of RsSUC1b in Radish (Raphanus sativus L.)

Horticulturae, 2022
In most higher plants, sucrose is the significant form of carbohydrate for long-distance transportation. Sucrose transporters/sucrose carriers (SUTs/SUCs) are involved in the loading and unloading of sucrose in phloem and play an important role in the ...
Xiaofeng Zhu, Xiaoli Zhang, Yang Cao, Ruixian Xin, Yinbo Ma, Lun Wang, Liang Xu, Yan Wang, Rui Liu, Liwang Liu   +9 more
doaj   +1 more source

Partition Decoupling for Multi-gene Analysis of Gene Expression Profiling Data [PDF]

, 2011
We present the extention and application of a new unsupervised statistical learning technique--the Partition Decoupling Method--to gene expression data.
Braun, Rosemary, Leibon, Gregory, Pauls, Scott, Rockmore, Daniel   +3 more
core   +5 more sources

Consensus clustering and functional interpretation of gene-expression data [PDF]

, 2004
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters.
Kellam, P., Liu, X., Martin, Nigel, Orengo, C.A., Swift, S., Tucker, A., Vinciotti, V.   +6 more
core   +2 more sources

qPCR-based methods for expression analysis of miRNAs

BioTechniques, 2019
Several approaches for miRNA expression analysis have been developed in recent years. In this article, we provide an updated and comprehensive review of available qPCR-based methods for miRNA expression analysis and discuss their advantages and ...
Diego A Forero, Yeimy González-Giraldo, Luis J Castro-Vega, George E Barreto   +3 more
doaj   +1 more source