Results 121 to 130 of about 234,285 (301)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Computing edge version of metric dimension of certain chemical networks

Scientific Reports
In the modern digital sphere, graph theory is a significant field of research that has a great deal of significance. It finds widespread application in computer science, robotic directions, and chemistry.
Muhammad Umer Farooq, Muhammad Hussain, Ahmed Zubair Jan, Afraz Hussain Mjaeed, Mirwais Sediqma, Ayesha Amjad   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

METABOLÔMICA DE PLANTAS: MÉTODOS E DESAFIOS

Química Nova
Metabolomics has played a central role in various areas of plant sciences, offering new perspectives for the advancement of agriculture, drug discovery, chemical ecology and taxonomy.
Alan C. Pilon, Denise M. Selegato, Richard P. Fernandes, Paula C. P. Bueno, Danielle R. Pinho, Fausto Carnevale Neto, Rafael T. Freire, Ian Castro-Gamboa, Vanderlan S. Bolzani, Norberto P. Lopes   +9 more
doaj   +1 more source

Deep learning based detector for real-time facial expression recognition

, 2019
Automated Facial Expression Recognition (AFER) technology has become a hot topic in the field of pattern recognition. An accurate and fast real-time detection of facial expression could significantly bring benefits to important applications in many areas
Han, Wei Jie
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Detection of human emotions through facial expressions using hybrid convolutional neural network-recurrent neural network algorithm

Intelligent Systems with Applications
Cognitive science plays a pivotal role in deciphering human behavior by understanding and interpreting emotions prevalent in everyday life. These emotions manifest through various cues, including speech patterns, body language, and notably, facial ...
Haposan Vincentius Manalu, Achmad Pratama Rifai   +1 more
doaj   +1 more source

An Infant Facial Expression Recognition System Based on Moment Feature Extraction

, 2011
[[abstract]]This paper presents a vision-based infant surveillance system utilizing infant facial expression recognition software. In this study, the video camera is set above the crib to capture the infant expression sequences, which are then sent to ...
Fang, Chiung-Yao;Lin, H. W.;Chen, Sei-Wan
core