Results 121 to 130 of about 640,065 (273)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Evolution of cis- and trans-regulatory divergence in the chicken genome between two contrasting breeds analyzed using three tissue types at one-day-old

BMC Genomics, 2019
Background Gene expression variation is a key underlying factor influencing phenotypic variation, and can occur via cis- or trans-regulation. To understand the role of cis- and trans-regulatory variation on population divergence in chicken, we developed ...
Qiong Wang, Yaxiong Jia, Yuan Wang, Zhihua Jiang, Xiang Zhou, Zebin Zhang, Changsheng Nie, Junying Li, Ning Yang, Lujiang Qu   +9 more
doaj   +1 more source

Expression and regulatory asymmetry of retained Arabidopsis thaliana transcription factor genes derived from whole genome duplication

BMC Evolutionary Biology, 2019
Background Transcription factors (TFs) play a key role in regulating plant development and response to environmental stimuli. While most genes revert to single copy after whole genome duplication (WGD) event, transcription factors are retained at a ...
Nicholas L. Panchy, Christina B. Azodi, Eamon F. Winship, Ronan C. O’Malley, Shin-Han Shiu   +4 more
doaj   +1 more source

A key variant in the cis-regulatory element of flowering gene Ghd8 associated with cold tolerance in rice. [PDF]

, 2019
Variations in the gene promoter play critical roles in the evolution of important adaptive traits in crops, but direct links of the regulatory mutation to the adaptive change are not well understood.
Fan, Kai, Gong, Rong, Wang, Peng, Xiong, Yin, Yang, Ying, Yu, Sibin   +5 more
core  

Substrate-Mediated Regulation of Src Expression Drives Osteoclastogenesis Divergence

Genes
Background/Objectives: Glass, bone, and dentin are commonly applied substrates for osteoclast cultures; however, the impact of these substrates on osteoclastogenesis remains underexplored. This study aimed to address a significant gap in understanding how different substrates influence the process of osteoclastogenesis.
Bo Hu, Yiming Chen, Yuman Li, Chenyu Deng, Yuting Niu, Zhewen Hu, Yao Li, Shiyu Sun, Ying Huang, Xuliang Deng, Yan Wei   +10 more
openaire   +2 more sources

Divergence in expressing definiteness between Mandarin and Cantonese

Proceedings of the International Conference on Head-Driven Phrase Structure Grammar, 2015
In this paper, we model the dialectal variation in the expression of definiteness in Mandarin and Cantonese adopting the Head-Driven Phrase Structure Grammar (HPSG) framework (Pollard & Sag, 1994) and Minimal Recursion Semantics (MRS) (Copestake et al., 2005).
Joanna Ut-Seong Sio, Sanghoun Song
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Duplicate gene evolution and expression in the wake of vertebrate allopolyploidization

BMC Evolutionary Biology, 2008
Background The mechanism by which duplicate genes originate – whether by duplication of a whole genome or of a genomic segment – influences their genetic fates.
Evans Ben J, Ilieva Dora, Chain Frédéric JJ   +2 more
doaj   +1 more source

Exact Expressions for Kullback–Leibler Divergence for Univariate Distributions

Entropy
The Kullback–Leibler divergence (KL divergence) is a statistical measure that quantifies the difference between two probability distributions. Specifically, it assesses the amount of information that is lost when one distribution is used to approximate another.
Victor Nawa, Saralees Nadarajah
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source