Extended-Interval Gentamicin Dosing for Pulmonic Tularemia [PDF]
Case Reports in Infectious Diseases, 2019 Francisella tularensis is a Gram-negative coccobacillus that is rarely encountered in clinical practice. Patients can present with cutaneous, pulmonary, cardiac, mucous membrane, or gastrointestinal involvement.
Tyson Dietrich +3 more
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Extended-Interval Dosing of Aminoglycosides in Pediatrics: A Narrative Review
Journal of Pediatrics Review, 2015 Aminoglycosides (AGs) are frequently used in pediatric settings, especially for empiric treatment of early-onset neonatal sepsis. Although AGs are used for several decades, the optimum method of administration and their dosing schemes needs more ...
Ebrahim Salehifar, Mohammad Reza Rafati
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Long-term extended-interval teclistamab and talquetamab dosing without step-up dosing in previously treated multiple myeloma [PDF]
Experimental Hematology & OncologyTeclistamab (Tec) and talquetamab (Tal) are bispecific CD3 T-cell engagers targeting B-cell maturation antigen and G protein-coupled receptor, class C, group 5, member D, respectively, and have transformed how we treat relapsed/refractory multiple ...
Callee Brooks +8 more
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No increase of serum neurofilament light in relapsing-remitting multiple sclerosis patients switching from standard to extended-interval dosing of natalizumab [PDF]
Multiple Sclerosis Journal, 2022 Jan Lycke +2 more
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Pharmacodynamics of natalizumab extended interval dosing in MS. [PDF]
Neurol Neuroimmunol Neuroinflamm, 2020 To determine if the concentration and saturation of natalizumab (NTZ) administration at extended interval dosing (EID; every 5-8 weeks) over 18 months is able to be maintained in the range considered adequate to sustain the clinical efficacy of NTZ.In a cross-sectional assessment of patients with multiple sclerosis (MS) who received standard interval ...
Zhovtis Ryerson L +7 more
europepmc +4 more sources
Modeling the Efficacy of Natalizumab in Multiple Sclerosis Patients Who Switch From Every-4-Week Dosing to Extended-Interval Dosing [PDF]
Journal of Clinical Pharmacology, 2021 Ih Chang, Pei-Ran Ho
exaly +2 more sources
Pharmacokinetics of aminoglycoside antibiotics. Based on population pharmacokinetic data determination of the loading dose, maintenance dose and dosage interval [PDF]
Farmacja Polska, 2021 Aminoglycosides are natural or semisynthetic antibiotics derived from actinomycetes. They bind to the bacterial ribosome, leading to inhibition of protein synthesis.
Arkadiusz Gruchlik, Marcin Kochan
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Safety of extended interval dosing immune checkpoint inhibitors: a multicenter cohort study. [PDF]
J Natl Cancer Inst, 2023 Abstract Background Real-life spectrum and survival implications of immune-related adverse events (irAEs) in patients treated with extended interval dosing (ED) immune checkpoint inhibitors (ICIs) are unknown.
Cantini L +50 more
europepmc +7 more sources
Extended interval dosing of natalizumab: More evidence in support. [PDF]
NeurotherapeuticsToljan K, Conway DS.
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Adjusted dose regimens in dupilumab treatment for atopic dermatitis: Daily practice experiences
JEADV Clinical Practice, 2022 Background Clinical trials with dupilumab in atopic dermatitis (AD) patients showed a trend towards better effectiveness with a weekly or biweekly dosing interval, compared with extended dosing intervals.
Jill I. Olydam +4 more
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