Results 141 to 150 of about 25,533 (260)

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao   +20 more
wiley   +1 more source

Programmable and Reversible 3D‐to‐3D Shape Transformation: Hierarchical Multimodal Morphing Based on Liquid Crystal Elastomers

open access: yesAdvanced Science, EarlyView.
Hierarchical multimodal 3D‐to‐3D shape morphing is achieved in liquid crystal elastomer‐elastomer bilayers via programmable mismatch strains. Combining pre‐stretch and thermal actuation enables reversible transformations with non‐zero Gaussian curvature, empowering over 30 complex configurations for biomimetic camouflage, adaptive robotics, and dynamic
Jiayu Tian   +4 more
wiley   +1 more source

Calcium‐Ion Insertion Chemistry in Tunneled α‐MnO2 Cathodes for Calcium Metal Batteries

open access: yesAdvanced Science, EarlyView.
α‐MnO2 cathodes demonstrate distinct electrochemical behavior and Ca2+ storage capabilities depending on whether they are paired with activated carbon anodes or Ca metal anodes. Ca2+ insertion/extraction is only feasible when α‐MnO2 cathodes are cycled against Ca metal anodes.
Shuangshuang Cui   +7 more
wiley   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

open access: yesAdvanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li   +9 more
wiley   +1 more source

The concepts of irreversibility and reversibility in research on anthropogenic environmental changes. [PDF]

open access: yesPNAS Nexus
Buhr L   +7 more
europepmc   +1 more source

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