Results 61 to 70 of about 18,849,427 (268)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

SC Building Codes Council [PDF]

open access: yes, 2022
The Building Codes Council at the South Carolina Department of Labor, Licensing and Regulation publishes a newsletter with news articles about the agency and to promote compliance in construction and building ...
South Carolina Building Codes Council
core   +1 more source

Refactorisation methods for TTCN-3

open access: yesActa Polytechnica, 2007
In this paper we introduce automatic methods for restructuring source codes written in test description languages. We modify the structure of these sources without making any changes to their behavior. This technique is called refactorisation.
L. Eros, F. Bozoki
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Performance Analysis of a H-Darrieus Wind Turbine for a Series of 4-Digit NACA Airfoils

open access: yesEnergies, 2020
The purpose of this paper is to estimate the H-Darrieus wind turbine aerodynamic performance, aerodynamic blade loads, and velocity profiles downstream behind the rotor. The wind turbine model is based on the rotor designed by McDonnell Aircraft Company.
Krzysztof Rogowski   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Exotic symmetry breaking properties of self-dual fracton spin models

open access: yesPhysical Review Research
Fracton codes host unconventional topological states of matter and are promising for fault-tolerant quantum computation due to their large coding space and strong resilience against decoherence and noise.
Giovanni Canossa   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Time-Dependent Verification of the SPN Neutron Solver KANECS

open access: yesJournal of Nuclear Engineering
KANECS is a 3D multigroup neutronics code based on the Simplified Spherical Harmonics (SPN) approximation and the Continuous Galerkin Finite Element Method (CGFEM).
Julian Duran-Gonzalez   +1 more
doaj   +1 more source

Low-density parity-check codes and their rateless relatives

open access: yes, 2011
This survey guides the reader through the extensive open literature that is covering the family of low-density parity-check LDPC codes and their rateless relatives.
Sheng Chen   +5 more
core   +1 more source

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