Results 51 to 60 of about 19,987 (262)
The most general model used to describe conflict situations is the extensive form model, which specifies in detail the dynamic evolution of each situation and thus provides an exact description of ‘who knows what when’ and ‘what is the consequence of which’.
openaire +2 more sources
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
“MILITANCY” CONCEPT-SPHERE’S SEMIOLINGUISTIC ACTUALIZATION IN ADVERTISING DISCOURSE
The paper focuses on the clusters of signs that support semiosis of belligerency and contribute to actualization of the concept-sphere “Militancy” in creolized advertising texts.
Daria G. Kurenova, Andrey V. Olyanich
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
The efficiency of a power system is reduced when voltage drops and losses occur along the distribution lines. While the voltage profile across the system buses can be improved by the injection of reactive power, increased line flows and line losses could
Ikponmwosa Idehen +2 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Coarse Correlation in Extensive-Form Games
Coarse correlation models strategic interactions of rational agents complemented by a correlation device which is a mediator that can recommend behavior but not enforce it. Despite being a classical concept in the theory of normal-form games since 1978, not much is known about the merits of coarse correlation in extensive-form settings. In this paper,
Gabriele Farina +2 more
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Extensive-form game abstraction with bounds [PDF]
Abstraction has emerged as a key component in solving extensive-form games of incomplete information. However, lossless abstractions are typically too large to solve, so lossy abstraction is needed. All prior lossy abstraction algorithms for extensive-form games either 1) had no bounds on solution quality or 2) depended on specific equilibrium ...
Christian Kroer, Tuomas Sandholm
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Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source

