HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Increasing alignment of large language models with language processing in the human brain. [PDF]
Gao C +5 more
europepmc +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Neurodevelopmental commonalities in cognitive control networks for mathematics and reading in meta-analysis of 3308 participants. [PDF]
Ünal ZE +4 more
europepmc +1 more source
Learning Vocabulary through Extensive Reading: Word Frequency Levels and L2 Learners' Vocabulary Knowledge Level. [PDF]
Anna C-S Chang, Hsueh-chao Marcella Hu
openalex
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The Reading Anxiety Scale for children: Development and psychometric properties. [PDF]
Grills AE +5 more
europepmc +1 more source
Extensive Reading with Guidance
text A language learning mode called “word-focused extensive reading” has been proposed to facilitate word-usage learning. The user inputs a word in the computer program designed and implemented for reading to find its usage in the context of a sentence.
openaire
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Double Trouble: The First Reported Case of Evans Syndrome Following RSV Vaccination. [PDF]
Abu-Tineh M +3 more
europepmc +1 more source

