Results 91 to 100 of about 2,978,826 (285)
XDR TB in South Africa - What lies ahead?
South African Family Practice, 2007 The emergence of XDR TB coupled with the high prevalence of HIV/AIDS has intensified the need to identify new treatment strategies and accelerate research into antibiotics against XDR TB before the world is faced with a global public health crisis.
V. Thaver, Gboyega A. Ogunbanjo
doaj +1 more source
Emergence of extensively drug-resistant Haemophilus parainfluenzae in Switzerland
, 2013 Two homosexual men were colonized in the urethra with Haemophilus parainfluenzae nonsusceptible to ampicillin (MIC, 8 μg/ml), amoxicillin-clavulanate (MIC, 4 μg/ml), cefotaxime (MIC, 1.5 μg/ml), cefepime (MIC, 3 μg/ml), meropenem (MIC, 0.5 μg/ml ...
Tinguely, Regula +5 more
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Challenges and Controversies in Defining Totally Drug-Resistant Tuberculosis
Emerging Infectious Diseases, 2012 In March 2012, in response to reports of tuberculosis (TB) resistant to all anti-TB drugs, the World Health Organization convened an expert consultation that identified issues to be resolved before defining a new category of highly drug-resistant TB ...
Peter Cegielski +8 more
doaj +1 more source
Drug-resistant Tuberculosis [PDF]
Type: BacteriaAlso known as: TB, multidrug-resistant TB (MDR TB), or extensively drug-resistant TB (XDR TB), Mycobacterium tuberculosis (M. tuberculosis)About: TB is caused by the bacteria M. tuberculosis, and is among the most common infectious diseases
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Tuberculosis in Sudan: a study of Mycobacterium tuberculosis strain genotype and susceptibility to anti-tuberculosis drugs. [PDF]
, 2011 BACKGROUND: Sudan is a large country with a diverse population and history of civil conflict. Poverty levels are high with a gross national income per capita of less than two thousand dollars.
Bottomley, Christian +23 more
core +2 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
International Journal of Mycobacteriology, 2016 Objective/background: Increasing resistance to various first-line and second-line drugs has become a major concern in India. However, it is not known if some genotypes are more associated with second-line drug resistance. Thus, the main aim of this study
Syed Beenish Rufai +3 more
doaj +1 more source
, 2017 Risara Jaksuwan,1 Prasit Tharavichikul,2 Jayanton Patumanond,3 Charoen Chuchottaworn,4 Sakarin Chanwong,5 Saijai Smithtikarn,6 Jongkolnee Settakorn7 1Clinical Epidemiology Unit, 2Department of Microbiology, Faculty of Medicine, Chiang Mai University ...
Chanwong S +6 more
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