Results 101 to 110 of about 2,978,826 (285)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Prevalence of Extensively Drug-Resistant Tuberculosis: a Descriptive Study

open access: yesЭпидемиология и вакцинопрофилактика, 2018
Background. Extensively drug-resistant tuberculosis (XDR-TB) is a threat to community health. Goal. The estimation of the prevalence of extensively drug-resistant tuberculosis in Omsk region, along with the clinical and epidemiological description of ...
O. A. Pasechnik   +4 more
doaj   +1 more source

Successful Treatment of Extensively Drug-Resistant Acinetobacter baumannii Intracranial Infection with Meropenem and Cefoperazone Sodium Sulbactam: A Case Report [PDF]

open access: yes
Wenke Ma,1 Chao Zhang,1 Bei He,1 Xinwen Lv,1 Peng Luo2 1Department of Neurosurgery, Baoji Central Hospital, Baoji, Shaanxi, People’s Republic of China; 2Department of Neurosurgery, The First Affiliated Hospital of Air Force Medical University, Xi’an ...
Luo P, Lv X, Zhang C, He B, Ma W
core  

Risk Factors, Outcomes, and Predictions of Extensively Drug-Resistant Acinetobacter baumannii Nosocomial Infections in Patients with Nervous System Diseases

open access: yes, 2023
Li Huang,1– 3,* Jingyang Tang,1– 3,* Gang Tian,1– 3 Hualin Tao,1– 3 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, People’s Republic of China; 2Sichuan Province Engineering ...
Tang J, Li Z, Tian G, Tao H, Huang L
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Moxifloxacin resistance in the F15/LAM4/KZN extensively drug-resistant strain of Mycobacterium tuberculosis

open access: yes, 2014
Navisha Dookie, A Willem Sturm, Prashini Moodley Department of Infection Prevention and Control, Nelson R Mandela School of Medicine, School of Laboratory Medicine and Medical Science, College of Health Science, University of KwaZulu-Natal, Durban, South
Dookie N, Sturm AW, Moodley P
core  

Distribution of Extensively Drug-resistant Tuberculosis in the World Health Organization Regions of the World During 1990-2019 [PDF]

open access: yes
The rise of drug-resistant tuberculosis (TB) has become a significant public health concern, representing a threat to global TB control programs. Extensively drug-resistant TB (XDR-TB) accounts for approximately 9% of all drug-resistant cases, and its ...
Maryam KAZEMI   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Extensively Drug-Resistant (XDR) Enteric Fever in Children

open access: yesPakistan Journal of Medicine and Dentistry
Background: Typhoid and paratyphoid fevers are caused by Salmonella enterica subspecies serovars typhi (Salmonella typhi and Paratyphi) and the term enteric fever is generally used to describe both.
Sana Ashraf   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy