Novel six-month all oral treatment of pre-extensively drug-resistant tuberculosis in Canada: New treatment options present new implementation challenges. [PDF]
Connors W +4 more
europepmc +1 more source
ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad +6 more
wiley +1 more source
Pre-extensively drug-resistant tuberculosis of the spine in a previously healthy young adult: case report. [PDF]
Schreurs H +5 more
europepmc +1 more source
Evaluation of TBMDR® and XDRA® for the detection of multidrug resistant and pre-extensively drug resistant tuberculosis. [PDF]
Cho E +10 more
europepmc +1 more source
ABSTRACT The NAT2 gene encodes N‐acetyltransferase 2, an enzyme critically involved in the biotransformation of numerous xenobiotics and aromatic amines, including isoniazid, a cornerstone drug in tuberculosis therapy. Genetic polymorphisms in NAT2 lead to variable acetylation rates, clinically categorized as poor, intermediate, or rapid metabolizer ...
Nada Benyahya +6 more
wiley +1 more source
Dendritic cells in the lung cavities of extensively drug-resistant tuberculosis patients exhibit altered frequency and phenotype. [PDF]
Londt R +6 more
europepmc +1 more source
Beijing genotype of Mycobacterium tuberculosis is associated with extensively drug-resistant tuberculosis: A global analysis. [PDF]
Keikha M, Majidzadeh M.
europepmc +1 more source
Synthetic Ligands of Myeloid C‐Type Lectin Receptors
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley +1 more source
Perinatal transmission and cure of extensively drug-resistant tuberculosis in an infant. [PDF]
Singh V +6 more
europepmc +1 more source
Pyrosequencing for diagnosis of multidrug and extensively drug-resistant tuberculosis: A systemic review and meta-analysis. [PDF]
Getachew E +11 more
europepmc +1 more source

