Results 161 to 170 of about 23,332 (236)

Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa. [PDF]

Microb Genom, 2022
Oostvogels S, Ley SD, Heupink TH, Dippenaar A, Streicher EM, De Vos E, Meehan CJ, Dheda K, Warren R, Van Rie A.   +9 more
europepmc   +1 more source

Cerebral Venous Thrombosis in a Young Adult: Challenges in Diagnosing and Managing Risk Factors in a Resource‐Limited Setting

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cerebral venous thrombosis should be suspected in young patients with severe headache and seizures, even without clear risk factors. In resource‐limited settings, early imaging and prompt anticoagulation can significantly improve outcomes despite incomplete thrombophilia workup.
Filmon Tesfay, Lidya Mussie, Samuel Tekle, Estifanos Habteab   +3 more
wiley   +1 more source

Extensively Drug-Resistant Tuberculosis With Treatment-Limiting Mood Disorder: A Case of Complex Regimen Selection and Mental Health Challenges. [PDF]

Cureus
Mkrtchyan S.
europepmc   +1 more source

Treatment outcomes of patients with multidrug and extensively drug-resistant tuberculosis in Zhejiang, China. [PDF]

Eur J Med Res, 2021
Zhang MW, Zhou L, Zhang Y, Chen B, Peng Y, Wang F, Liu ZW, Wang XM, Chen SH.   +8 more
europepmc   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Risk Factors for Poor Outcomes Among Patients with Extensively Drug-Resistant Tuberculosis (XDR-TB): A Scoping Review. [PDF]

Infect Drug Resist, 2021
Varshney K, Anaele B, Molaei M, Frasso R, Maio V.   +4 more
europepmc   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

Interim efficacy and safety analysis of the regimen containing delamanid in the treatment of multidrug resistant/rifampicin-resistant/extensively drug-resistant tuberculosis: a single-arm, prospective, monocentric, observational study. [PDF]

BMC Infect Dis
Qin Y, Chen Y, Cai Q.
europepmc   +1 more source

Cost-effectiveness of bedaquiline, pretomanid and linezolid for treatment of extensively drug-resistant tuberculosis in South Africa, Georgia and the Philippines. [PDF]

BMJ Open, 2021
Gomez GB, Siapka M, Conradie F, Ndjeka N, Garfin AMC, Lomtadze N, Avaliani Z, Kiria N, Malhotra S, Cook-Scalise S, Juneja S, Everitt D, Spigelman M, Vassall A.   +13 more
europepmc   +1 more source

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni, Ebba Qviberg, Edward Chaloner, Hayley Lavender, Maisem Laabei   +4 more
wiley   +1 more source