Results 51 to 60 of about 3,057,829 (262)
Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]
, 2013 Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.Nalini Mehta, Joaquín Rullás, Minick, Douglas J, María Martínez-Hoyos, Pallen, Mark J., Rebollo-López María José, Sousa, Verónica, Modesto J. Remuiñán (291058), Chrystala Constantinidou (161352), Johnson Afari, Pérez-Herrán Esther, Jorge Esquivias (403585), Jiménez, Elena, Jiménez Elena, Dow, David J, Constantinidou Chrystala, Fátima Ortega-Muro, Remuiñán, Modesto J, Esquivias Jorge, Fátima Ortega-Muro (403586), Mendoza-Losana, Alfonso, Pallen, Mark J, Lluís Ballell (2196634), Rullás, Joaquín, Besra, Gurdyal S; id_orcid, Vickey L Spivey, María Teresa Fraile-Gabaldón, Carolina González, Sousa Verónica, González, Carolina, Mónica Cacho, Ballell, Lluís, Martínez-Hoyos María, Elena Jiménez (47475), Carolina González (321712), María José Rebollo-López, Pérez-Herrán, Esther, Johnson Afari (403583), Esquivias, Jorge, Spivey, Vickey L., Nicholas J. Loman (126279), Verónica Sousa, Mehta, Nalini, Rebollo-López, María José, Cacho Mónica, Angulo-Barturen, Iñigo, Spivey Vickey L., Barros, David, Vickey L. Spivey (291055), Spivey, Vickey L, Esther Pérez-Herrán, Minick Douglas J., Alfonso Mendoza-Losana (403592), Cacho, Mónica, Nicholas J Loman, Lluís Ballell, Alfonso Mendoza-Losana, Besra, Gurdyal S., Dow David J., Loman, Nicholas J., Mehta Nalini, David J. Dow (403582), Afari, Johnson, Nicholas Cammack (403593), Rullás Joaquín, Iñigo Angulo-Barturen, Esther Pérez-Herrán (403580), Mark J Pallen, Loman, Nicholas J, Carlos Alemparte, Constantinidou, Chrystala, Alemparte Carlos, Fraile-Gabaldón, María Teresa, David J Dow, Douglas J Minick, Remuiñán, Modesto J., Besra Gurdyal S., Gurdyal S. Besra (37660), Remuiñán Modesto J., Chrystala Constantinidou, Mark J. Pallen (8904), Cammack, Nicholas, Ortega-Muro, Fátima, Mendoza-Losana Alfonso, Joaquín Rullás (5654542), Dow, David J., Angulo-Barturen Iñigo, Loman Nicholas J., Nalini Mehta (403584), Alemparte, Carlos, Minick, Douglas J., David Barros (291059), María Teresa Fraile-Gabaldón (403587), Modesto J Remuiñán, Barros David, María Martínez-Hoyos (403581), Mónica Cacho (403589), Cammack Nicholas, Ortega-Muro Fátima, Elena Jiménez, Carlos Alemparte (291057), Afari Johnson, Gurdyal S Besra, Fraile-Gabaldón María Teresa, Martínez-Hoyos, María, David Barros, Iñigo Angulo-Barturen (47469), Ballell Lluís, González Carolina, Douglas J. Minick (403588), Jorge Esquivias, María José Rebollo-López (403590), Pallen Mark J., Nicholas Cammack, Verónica Sousa (403591) +114 morecore +1 more sourceExtensively drug resistant tuberculosis in Mali: a case report
BMC Research Notes, 2017 Background Drug resistant tuberculosis presents a major public health challenge. Case presentation We present here the first two patients diagnosed with extensively drug resistant tuberculosis in Bamako, Mali.Bassirou Diarra, Yacouba Toloba, Bakary Konate, Moumine Sanogo, Antieme Combo Georges Togo, Fatimata Camara, Gaoussou Berthe, Dianguina Soumaré, Bocar Baya, Drissa Goita, Yeya dit Sadio Sarro, Mamoudou Maiga, Michael Belson, Susan Orsega, Sounkalo Dao, Robert L. Murphy, Sophia Siddiqui, Bouke C. de Jong, Seydou Doumbia, Souleymane Diallo +19 moredoaj +1 more sourceLinezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.
, 2012 BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.Rose, PC, Hallbauer, UM, Hesseling, AC, Schaaf, HS, Seddon, JA +4 morecore +1 more sourceNew drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]
, 2008 Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.Willcox, Benjamin, Gurdyal S Besra, Bhatt, Apoorva; id_orcid, Dover, LG, Apoorva Bhatt, Dover, Lynn, Besra, Gurdyal; id_orcid, Besra, Gurdyal, Bhatt, Apoorva, Lynn G Dover, Bhowruth, Veemal, Veemal Bhowruth, Benjamin E Willcox +12 morecore +1 more sourceCulture conversion at six months in patients receiving bedaquiline- and delamanid-containing regimens for the treatment of multidrug-resistant tuberculosis
International Journal of Infectious Diseases, 2021 Rifampicin-resistant/multidrug-resistant (RR/MDR) and extensively drug-resistant (XDR) strains of M. tuberculosis (TB) are serious public health problem in Kazakhstan.Shynar M. Maretbayeva, Anar S. Rakisheva, Malik M. Adenov, Lyazzat T. Yeraliyeva, Yerkebulan Zh. Algozhin, Assel T. Stambekova, Elmira A. Berikova, Askar Yedilbayev, Michael L. Rich, Kwonjune J. Seung, Assiya M. Issayeva +10 moredoaj +1 more sourceCXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization
Advanced Science, EarlyView.In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu +8 morewiley +1 more sourceThe infectiousness of tuberculosis patients coinfected with HIV [PDF]
, 2008 The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.Ticona, E., Navincopa, Marcos, Gilman, RH, Gilman, R.H., Caviedes, L, Carlton A Evans, Patricia Sheen, Caviedes, L., Gilman Robert H, Gonzalez Armando, Ticona, Eduardo, Gonzalez, A, Moore, David AJ, Sheen, Patricia, Robert H Gilman, Caviedes Luz, Sheen Patricia, Armando Gonzalez, Navincopa, M., Catherine J Noakes, Sheen, P, Jon S Friedland, A Roderick Escombe, Gilman, Robert H, Martínez Carlos, Pan, W., Martinez, C, Escombe, AR, William Pan, Luz Caviedes, Evans, Carlton A, Gonzalez, A., Friedland, Jon S, Navincopa, M, Pan, W, Escombe A. Roderick, Noakes Catherine J, Noakes, Catherine J, Martínez, Carlos, Noakes, CJ, Evans, C.A., Evans, CA, Carlos Martínez, Moore, D.A.J., Caviedes, Luz, Moore, DAJ, Escombe, A.R., Friedland, J.S., Pan, William, Ticona, E, Moore David A. J, Navincopa Marcos, Pan William, David A J Moore, Friedland Jon S, Noakes, C.J., Sheen, P., Friedland, JS, Martinez, C., Ticona Eduardo, Marcos Navincopa, Evans Carlton A, Gonzalez, Armando, Eduardo Ticona, Escombe, A Roderick +64 morecore +2 more sourcesClinical periodontal diagnosis
Periodontology 2000, EarlyView., 2023 Abstract
Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang +5 morewiley +1 more sourceEfficacy and safety data on pretomanid for drug-resistant TB
IJTLD OpenOBJECTIVE: To summarise the efficacy and safety of pretomanid (Pa) based regimens in patients with drug-resistant TB (DR-TB). METHODS: We included clinical trials, operational research and observational studies reporting the efficacy and safety of Pa ...H.T.T. Thuy, C. Padmapriyadarsini, C. Chuchottaworn, S. Foraida, S. Hadigal, A.R. Birajdar +5 moredoaj +1 more source
