Results 101 to 110 of about 2,105,379 (312)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A Topology of Everyday Constellations de Georges Teyssot

Cuadernos de Proyectos Arquitectónicos, 2019
Resumen En el libro, A topology of everyday constellations, Georges Teyssot expone los temas que va persiguiendo hace décadas, manteniendo su ya conocido registro erudito y denso. Como un flâneur intenta desentrañar la espesura compleja de las tramas de
Ana Sofía Pereira
doaj  

Assessing Stereo Camera Applicability for Digital Monitoring of Cattle Exterior

Сельскохозяйственные машины и технологии
The paper highlights the substantial potential for digitalization in animal husbandry. Current applications of digital technologies include replacing manual data collection on animal phenotypes, particularly linear measurements of physical traits.
S. S. Yurochka, D. Yu. Pavkin, A. R. Khakimov, P. S. Berdyugin, S. O. Bazaev   +4 more
doaj   +1 more source

Modelo probabilístico de pronostico por punto

Geofísica Internacional, 1986
Tratamos un modelo en estrategia secuencial adaptiva, con estadística Bayesiana y función de costos de mínimo cuadrado. Se utilizan los datos de isohipsas de a lo más diez días en secuencia y se pronostica el valor que tomará la isohipsa exactamente ...
T. Castro, L. le Moyne, E. Villanueva
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Predicción del campo de las isohipsas, a partir de la solución de una ecuación tipo elíptica por serie de Fourier

Geofísica Internacional, 1985
Se expresa la función de corriente como una doble serie de Fourier, en una ecuación de tipo elíptica, y se transforma en un conjunto de ecuaciones lineales para los coeficientes.
T. Castro, L. Le Moyne H., E. Villanueva U.   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

HETEROGENEIDAD Y DESIGUALDAD EN EL MODELO COSTARRICENSE: LAS TRES MEJORES PRÁCTICAS LATINOAMERICANAS DE FOMENTO FISCAL A LA INVERSIÓN PRIVADA EN I+D+i

Revista Nacional de Administración, 2014
Costa Rica tiene un modelo de desarrollo fundado en la apertura comercial. Tratados preferenciales de comercio y exitosa atracción de inversión extranjera directa (IED) dieron lugar a un crecimiento acelerado de exportaciones que mejoraron las ...
VELIA GOVAERE VICARIOLI, HELLEN RUIZ HIDALGO   +1 more
doaj   +1 more source