Results 31 to 40 of about 2,105,298 (255)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Explosive entrainment in Arnold tongues

open access: yesPhysical Review Research
Entrainment refers to the unidirectional synchronization of an oscillator system to external periodic forcing, with phase-locking regions forming Arnold tongues.
Jiangsheng Wang   +6 more
doaj   +1 more source

The intrinsic rarity of equilibrium response in stratigraphic processes

open access: yesGeosystems and Geoenvironment
Conventional sequence stratigraphy is based, explicitly or implicitly, on the hypothesis that steady external forcing results in a steady stratigraphic configuration (equilibrium response), so that an unsteady stratigraphic configuration is usually ...
Junhui Wang, Tetsuji Muto
doaj   +1 more source

Low-Temperature Hydrothermal Systems Response to Rainfall Forcing: An Example From Temperature Time Series of Fumaroles at La Soufrière de Guadeloupe Volcano

open access: yesFrontiers in Earth Science, 2022
Volcanoes with highly-developed and shallow hydrothermal systems may be subject to sudden increases of their surface steam emission at vents in response to either deep forcing (e.g. increase of heat flux coming from the magma chamber) or external forcing
Jean de Bremond d’Ars   +1 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Major factors influencing local dust radiative forcing [PDF]

open access: yes, 2008
In conclusion, it is shown in this paper that surface albedo variations over desert regions can have a significant influence on the solar and net radiative forcing of desert dust.
Otto, Sebastian   +4 more
core  

Characterizing Compound Inland Flooding Mechanisms and Risks in North America Under Climate Change

open access: yesEarth's Future
Compound inland flooding (CIF) arises from the concurrent interaction of multiple hydrometeorological drivers. In this study, we characterize key CIF events across North America, including two preconditioned events, rain‐on‐snow (ROS) and saturation ...
Mohammad Fereshtehpour   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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