Results 121 to 130 of about 313,784 (306)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

The readiness–preparedness bias: recalibrating monitoring logic

open access: yesFrontiers in Physiology
This perspective argues that readiness monitoring metrics may be given disproportionate decision-weight relative to sport-specific preparedness indicators when daily load choices are made for athletes whose chronic physical capacity remains below the ...
Karol Kruczek   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Differences in external loads of different pitch types in Chinese male college baseball players

open access: yesFrontiers in Sports and Active Living
BackgroundIn baseball, monitoring player load solely through pitch count and innings overlooks the variability introduced by different pitch types. This study analyzed differences in external load, measured as Player Load, across various pitch types ...
Shenglei Qin   +3 more
doaj   +1 more source

SETLr: the semantic extract, transform, and load-r

open access: yes, 2018
Semantic Extract, Transform, and Load-er (SETLr) is a flexible, scalable tool for providing semantic interpretations to tabular, XML, and JSON-based data from local or web files.
McCusker, Jamie   +4 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The effect of substitutions on match running performance and tactical-technical performance in the Qatar 2022 World Cup

open access: yesEuropean Journal of Human Movement
This study aimed to analyze the impact of substitutions on players match running and tactical technical performance during the FIFA World Cup Qatar 2022, considering the type of substitutions.
Borja Sanabria-Pino   +5 more
doaj  

Reliability of a novel neck external loading dynamometer

open access: yesJournal of Biomechanics
Cervistab is an electro-pneumatic device that produces flexion push-loading events in an ecological rugby position (i.e. similar to on-pitch position) to assess neck extensors muscle response to a flexion perturbation. This response is important for preventing head/neck injuries in Rugby, however there is a clear lack of validated devices in the ...
Marc Julia   +5 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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