Results 101 to 110 of about 1,262,881 (342)

Effects of additional external load manipulation on perceptual and physiological responses during exergame

Motriz: Revista de Educacao Fisica, 2018
Aims: This study tested whether performing exergames with and without additional external load could induce to different internal load demand for young adults.
Renata Wolf, André Luiz Félix Rodacki, Mateus Corrêa Silveira, Eddy Krueger, Gleber Pereira   +4 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Organization of Students and Total Task Time: External and Internal Load Recorded during Motor Activity [PDF]

, 2021
Juan M. García-Ceberino, Sebastián Feu Molina, Antonio Antúnez Medina, Sérgio J. Ibáñez   +3 more
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Measurement of Training and Competition Loads in Elite Rhythmic Gymnastics: A Systematic Literature Review

Applied Sciences
In the long-term performance development of rhythmic gymnasts aged 16–17, athletes enter a high-performance training phase, marked by increased training loads and preparation for international competitions.
Katarzyna Sterkowicz-Przybycień, Tijana Purenović-Ivanović   +1 more
doaj   +1 more source

The role of structural viscoelasticity in deformable porous media with incompressible constituents: applications in biomechanics

, 2017
The main goal of this work is to clarify and quantify, by means of mathematical analysis, the role of structural viscoelasticity in the biomechanical response of deformable porous media with incompressible constituents to sudden changes in external ...
Bociu, Lorena, Guidoboni, Giovanna, Sacco, Riccardo, Verri, Maurizio   +3 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Structure and Thermodynamical Properties of Zirconium hydrides from first-principle

, 2011
Zirconium alloys are used as nuclear fuel cladding material due to their mechanical and corrosion resistant properties together with their favorable cross-section for neutron scattering.
Ackland, Chen, Coleman, Domain, Domain, Fisher, Hill, Holliger, Ikehata, Ma, Ma, Monkhorst, Mortensen, Myers, Niedzwiedz, Northwood, Perdew, Shih, Souvatzis, Togo, Udagawa, Yamanaka, Zhao, Zhu, Zuzek   +24 more
core   +1 more source