Results 81 to 90 of about 304,985 (264)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The Impact of a Congested Match Schedule (Due to the COVID-19 Lockdown) on Creatine Kinase (CK) in Elite Football Players Using GPS Tracking Technology

Sensors
The aim was to analyse the consequences of a congested schedule (due to the COVID-19 lockdown) on creatine kinase (CK) in elite football players using GPS tracking technology.
Jorge Garcia-Unanue, Antonio Hernandez-Martin, David Viejo-Romero, Samuel Manzano-Carrasco, Javier Sanchez-Sanchez, Leonor Gallardo, Jose Luis Felipe   +6 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Variability in the Load of Professional Basketball Referees during Competition

Applied Sciences
Monitoring the demands on basketball referees is essential for optimizing their performance and reducing the risk of injuries. This study aimed to analyze the workload experienced by elite basketball referees during official games.
Sergio José Ibáñez, Alejandro Vaquera, David Mancha-Triguero, Adrián Escudero-Tena   +3 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Analysis of the competitive load in u16 handballers as a function of the final result

E-balonmano.com: Revista de Ciencias del Deporte, 2018
The current trends in team sports training are based on the reproduction of the specific performance of the game in a non-competitive context. A study of the characteristics of the competition is required to gather the information necessary to design and
David Mancha Triguero, María Reina, Belén Baquero, Javier García-Rubio, Sergio J. Ibáñez   +4 more
doaj  

High-Speed Running and Sprinting Thresholds in Elite Female Team Sports: A Systematic Review

Applied Sciences
Over the past decade, participation in female team sports has increased significantly, leading to greater interest in monitoring their training and competition load using wearable technology.
Raúl Nieto-Acevedo, Alfonso de la Rubia, Enrique Alonso-Pérez-Chao, Moisés Marquina Nieto, Carlos García-Sánchez   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A Dual-Tech Approach to Measuring Defensive Physical Demands in Basketball Pick-and-Rolls During Official Games: Inertial Sensors and Video Analysis

Applied Sciences
This study aimed to quantify the physical load of defensive pick-and-roll (PnR) actions according to court location (middle or side), defensive option employed (switch, drop/ice, or trap), and effectiveness (successful or unsuccessful) during official ...
Abdelaziz Qarouach, Daniele Conte, Pierpaolo Sansone, Marco Pernigoni   +3 more
doaj   +1 more source