Results 91 to 100 of about 1,262,881 (342)

Load control system [PDF]

open access: yes
The load control system developed for the shuttle external structural tests is described. The system consists of a load programming/display module, and a load control module along with the following hydraulic system components: servo valves, dump valves,
Grosse, J. C.
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Pressure wave propagation in a shaken granular bed [PDF]

open access: yes, 2005
Pressure waves in a granular material travel through particle contact points and are primarily transmitted by the "force chains" that carry most of the load in a granular medium.
Brennen, Christopher E.   +1 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Cracking Piles of Brittle Grains

open access: yes, 1998
A model which accounts for cracking avalanches in piles of grains subject to external load is introduced and numerically simulated. The stress is stochastically transferred from higher layers to lower ones.
C. C. Mounfield   +30 more
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

External Load Variables Affect Recovery Markers up to 72 h After Semiprofessional Football Matches

open access: yesFrontiers in Physiology, 2019
Background: Player tracking devices are commonly used to monitor external load from training and matches in team sports. Yet, how the derived external load variables relate to fatigue and recovery post-training or post-match is scarcely researched.
Håvard Wiig   +5 more
doaj   +1 more source

Perspective of Dose and Response for Individualized Physical Exercise and Training Prescription

open access: yesJournal of Functional Morphology and Kinesiology, 2020
Physical interventions are used to increase physical (sports) performance and considered as effective low-cost strategies in the fields of healthcare, disease or injury prevention, and medical treatment.
Thomas Gronwald   +3 more
doaj   +1 more source

Association between external training loads and injury incidence during 44 weeks of military training [PDF]

open access: hybrid, 2023
Steven Powell   +8 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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