Results 111 to 120 of about 313,784 (306)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Coupling between the Output Force and Stiffness in Different Variable Stiffness Actuators
Actuators, 2014 The fundamental objective in developing variable stiffness actuators is to enable the actuator to deliberately tune its stiffness. This is done through controlling the energy flow extracted from internal power units, i.e., the motors of a variable ...
Amir Jafari
doaj +1 more source
The effect of different motocross circuit typologies on internal load and external load responses in riders [PDF]
Background: Several physical and physiological changes occur during a motocross race, mainly due to the type of circuits, and therefore the impact of different types of circuits on training load responses continues to need to be fully clarified ...
Rodrigues, Joana
core +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Frontiers in Sports and Active LivingIntroductionThe evaluation of the physical load of the training process is paramount not only as an attempt to decrease injury rates or to verify the effectiveness of interventions but mostly to find the best way to stimulate the players and optimise ...
Ivan Baptista +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Circadian Rhythms and External Load Measures in Professional Soccer Players
Applied SciencesThe aim of the present study was to examine the potential effects of circadian rhythmicity on specific external load metrics in professional male soccer players. Twenty players, members of a Greek Super League team, participated in the study.
Nikolaos E. Koundourakis +5 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Frontiers in Sports and Active LivingThe aim of this study was to determine if positional Worst-Case-Scenarios (WCS) during official games (OG) are replicated in Large-Sided Games (LSG) with a similar Area per Player (ApP) as OG.
Lukas Herzig +6 more
doaj +1 more source
The effects of self-report cognitive failures and cognitive load on antisaccade performance
, 2011 Individuals reporting high levels of distractibility in everyday life show impaired performance in standard laboratory tasks measuring selective attention and inhibitory processes.
Nazanin Derakshan +8 more
core +1 more source