Results 61 to 70 of about 1,250,327 (305)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Muscle-Specific Effective Mechanical Advantage and Joint Impulse in Weightlifting [PDF]

, 2016
Lifting greater loads during weightlifting exercises may theoretically be achieved through increasing the magnitudes of net joint impulses or manipulating the joints’ effective mechanical advantage (EMA).
Harris, Chad, Kipp, Kristof
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Uncovering the Latent Components of Physical Performance in Professional Soccer: Evidence from the Turkish First Division

Journal of Functional Morphology and Kinesiology
Background: Physical performance in soccer is usually described through isolated indicators such as total distance or sprint frequency, which may overlook the broader structure of match demands. Purpose: This study aimed to identify the latent components
Spyridon Plakias, Dimitris Tsaopoulos, Themistoklis Tsatalas, Giannis Giakas   +3 more
doaj   +1 more source

Training load monitoring by position and task in professional men´s basketball

E-balonmano.com: Revista de Ciencias del Deporte, 2021
The aim of this study was to analyze the training load of the different tasks of a professional basketball team, based on the tasks and player positions. A total of 10 professional basketball players participated (Mage = 23.70; SD = 2.26) who carried out
José Carlos Ponce Bordón, Iván Ramírez Bravo, Miguel Ángel López Gajardo, Jesús Díaz García   +3 more
doaj  

Divertor Heat Load in ASDEX Upgrade L-Mode in Presence of External Magnetic Perturbation [PDF]

, 2017
Power exhaust is one of the major challenges for a future fusion device. Applying a non-axisymmetric external magnetic perturbation is one technique that is studied in order to mitigate or suppress large edge localized modes which accompany the high ...
Eich, Thomas, Faitsch, Michael, Herrmann, Albrecht, Sieglin, Bernhard, Suttrop, Wolfgang, Team, the ASDEX Upgrade   +5 more
core   +3 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Inverse problem of photoelastic fringe mapping using neural networks [PDF]

, 2007
This paper presents an enhanced technique for inverse analysis of photoelastic fringes using neural networks to determine the applied load. The technique may be useful in whole-field analysis of photoelastic images obtained due to external loading, which
Bharath R, Bishop C, Cameron A Danial R Durrant-White H, Eghtedari F, Freeman J, Gurtej S Grewal, Patterson D, Quiroga J, Ramesh K, Ramesh K, Venketesh N Dubey, Vishay Measurement Groups   +11 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source