Results 41 to 50 of about 616,950 (264)

Environmental liability insurance and corporate ESG performance: Evidence from China

open access: yesJournal of Economics and Management
Aim/purpose – This study examines the role of market-based environmental instruments in corporate governance by assessing the association between Environmental Liability Insurance (ELI) and corporate environmental, social, and governance (ESG ...
Zhai Hui
doaj   +1 more source

InSAR Observation and Numerical Modeling of the Earth-Dam Displacement of Shuibuya Dam (China)

open access: yesRemote Sensing, 2016
How to accurately determine the mechanical parameters of rockfill is one of the key issues of concrete-face rockfill dams. Parameter back-analysis using internal or external monitoring data has been proven to be an efficient way to solve this problem ...
Wei Zhou   +3 more
doaj   +1 more source

An analysis of internal and external feedback in self-regulated learning activities mediated by self-regulated learning tools and open learner models

open access: yesInternational Journal of Educational Technology in Higher Education, 2020
In self-regulated learning (SRL), students organize, monitor, direct, and regulate their learning. In SRL, monitoring plays a critical role in generating internal feedback and thus adopting appropriate regulations.
Chih-Yueh Chou, Nian-Bao Zou
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Monitoring of external respiratory recovery during postmedication (literature review)

open access: yesВестник анестезиологии и реаниматологии
Introduction. Monitoring of external respiration after general anesthesia is of interest for predicting complications associated specifically with delayed recovery of components of external respiration due to the residual effect of drugs.
O. E. Kutina   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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