Results 51 to 60 of about 570,966 (263)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Quality assessment: importance of external evaluation and monitoring

Avances en Supervisión Educativa, 2007
The aim of this paper is to illustrate the steps to develop a quality assessment and analyse the importance of external assessment and follow-up in a university.
Juan José Tarí Guilló, Susana Amalia de Juana Espinosa, Jerónimo Manuel Mora Pascual   +2 more
doaj  

Multilevel sensor for monitoring external and internal environment of eggs

Poultry Science
: Although it is well known that incubation environment has a great influence on embryogenesis and post-hatching performance of birds, not much is known about how external thermal, sound and light stimuli are isolated by eggshells and perceived by ...
Sérgio Luís de Castro Júnior, Glauber da Rocha Balthazar, Robson Mateus Freitas Silveira, Iran José Oliveira da Silva   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Internal and external signal processing in patients with panic disorder: An event-related potential (ERP) study.

PLoS ONE, 2018
Self-absorption describes a pathological tendency towards the internal mental world (internalization) that often conflicts with the accurate monitoring of the external world. In performance monitoring, an augmented electrophysiological response evoked by
Christian Valt, Dorothea Huber, Ingrid Erhardt, Birgit Stürmer   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Relationship of Individual Athlete External Load, Session Rating of Perceived Exertion, and Athlete Playing Status Across a Collegiate Women’s Basketball Season

Sports
External (EL) and internal (IL) load are commonly used methods used to quantify training load in team sports. Playing time and playing position may influence the training loads for specific athletes throughout a season.
Faith S. A. Brown, Jennifer B. Fields, Andrew R. Jagim, Erica L. King, Robert E. Baker, Angela Miller, Margaret T. Jones   +6 more
doaj   +1 more source

Automated external cardioversion defibrillation monitoring in cardiac arrest: a randomized trial

Trials, 2008
Background In-hospital cardiac arrest has a poor prognosis despite active electrocardiography monitoring. The initial rhythm of approximately 25% of in-hospital cardiopulmonary resuscitation (CPR) events is pulseless ventricular tachycardia/ventricular ...
Norvel Robert, House Dorothy, Veledar Emir, Bloom Heather, Ali Bakhtiar, Dudley Samuel C, Zafari A Maziar   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source