Results 31 to 40 of about 6,595,667 (193)

Exposure to Violence and Neglect Images Differentially Influences Fear Learning and Extinction

open access: yes, 2020
The mechanisms by which exposure to adversity contributes to psychopathology development are poorly understood. Recent models link experiences of threat of harm and deprivation to psychopathology via disruptions in learning mechanisms underlying fear ...
Waters, Allison M   +2 more
core   +1 more source

L-DOPA modulates activity in the vmPFC, nucleus accumbens, and VTA during threat extinction learning in humans

open access: yeseLife, 2021
Learning to be safe is central for adaptive behaviour when threats are no longer present. Detecting the absence of an expected threat is key for threat extinction learning and an essential process for the behavioural treatment of anxiety-related ...
Roland Esser   +3 more
doaj   +1 more source

Extinction of cue-evoked drug-seeking relies on degrading hierarchical instrumental expectancies [PDF]

open access: yes, 2014
There has long been need for a behavioural intervention that attenuates cue-evoked drug-seeking, but the optimal method remains obscure. To address this, we report three approaches to extinguish cue-evoked drug-seeking measured in a Pavlovian to ...
Rose, Abigail K.   +31 more
core   +1 more source

Functional and Dysfunctional Neuroplasticity in Learning to Cope with Stress

open access: yesBrain Sciences, 2020
In this brief review, we present evidence of the primary role of learning-associated plasticity in the development of either adaptive or maladaptive coping strategies.
Simona Cabib   +4 more
doaj   +1 more source

Modulation of the extinction of fear learning

open access: yesBrain Research Bulletin, 2014
We review recent work on extinction learning with emphasis on its modulation. Extinction is the learned inhibition of responding to previously acquired tasks. Like other forms of learning, it can be modulated by a variety of neurotransmitter systems and behavioral procedures.
Jociane C, Myskiw   +2 more
openaire   +2 more sources

Concurrent extinction does not render appetitive conditioning context specific [PDF]

open access: yes, 2011
In an experiment with rats, an appetitive conditioning method was used to investigate the generality of the hypothesis that extinction should arouse attention to contextual cues, resulting in all learning in that context becoming context specific.
Samuel P. Léon   +5 more
core   +1 more source

Neuroscience Informed Prolonged Exposure Practice: Increasing Efficiency and Efficacy Through Mechanisms

open access: yesFrontiers in Behavioral Neuroscience, 2018
Prolonged exposure (PE) is an empirically supported efficacious treatment for posttraumatic stress disorder (PTSD). In this focused review, we briefly review the neurobiological networks in PTSD relevant to PE, discuss the theoretical basis of PE, review
Monika M. Stojek   +6 more
doaj   +1 more source

Theta coupling within the medial prefrontal cortex regulates fear extinction and renewal

open access: yesiScience, 2022
Summary: Fear learning, and its extinction, are fundamental learning processes that allow for a response adaptation to aversive events and threats in the environment.
Cong Wang   +3 more
doaj   +1 more source

Cholinergic regulation of fear learning and extinction [PDF]

open access: yesJournal of Neuroscience Research, 2016
Cholinergic activation regulates cognitive function, particularly long‐term memory consolidation. This Review presents an overview of the anatomical, neurochemical, and pharmacological evidence supporting the cholinergic regulation of Pavlovian contextual and cue‐conditioned fear learning and extinction.
Marlene A, Wilson, Jim R, Fadel
openaire   +2 more sources

Vagally mediated heart rate variability and safety learning: Effects of instructions and number of extinction trials [PDF]

open access: yes, 2019
Extinction of conditioned fear serves as a laboratory model for the mechanism of action underlying exposure treatment with patients suffering from anxiety disorders.
Jörg König   +11 more
core   +1 more source

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