Results 81 to 90 of about 173,465,999 (294)

Unconventional programmes to promote experiences with urban nature in Berlin

open access: yesPeople and Nature
As more people live in cities, there is growing concern about the decline in human–nature interactions, which negatively affect health and engagement with conservation efforts.
Ingo Kowarik   +2 more
doaj   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

JackVJohnson/Genome-size-extinction-risk-FE: Genome-size-extinction-risk-FE

open access: yes, 2022
Code and data for "Genome size does not influence extinction risk in the world's amphibians" published in Functional Ecology ...
JackVJohnson
core   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok   +13 more
wiley   +1 more source

Use of Extinction Corrections in Neutron Diffraction Experiments [PDF]

open access: yesAustralian Journal of Physics, 1988
The study of extinction by neutrons reveals many features of the extinction problem: theory and practical cases, polarised and unpolarised neutron cases. Special attention is given to the usual extinction corrections for neutron diffraction experiments, showing the relative importance of structure factor, wavelength, Lorentz factor, mosaic and the path
openaire   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

open access: yesAdvanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee   +5 more
wiley   +1 more source

Negative symbolism of wildlife shapes human–nature coexistence: The plight of owls in Nigeria

open access: yesPeople and Nature
Human–wildlife coexistence in culturally diverse landscapes requires understanding how socio‐cultural processes shape perceptions and behaviours towards conservation‐priority species.
Iniunam Aniefiok Iniunam   +5 more
doaj   +1 more source

Involvement of dopamine D1/D5 and D2 receptors in context-dependent extinction learning and memory reinstatement

open access: yesFrontiers in Behavioral Neuroscience, 2016
Dopamine contributes to the regulation of higher order information processing and executive control. It is important for memory consolidation processes, and for the adaptation of learned responses based on experience.
Marion Agnes Emma Andre   +1 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang   +12 more
wiley   +1 more source

Molecular Preorganization Unlocks Reversible Solid‐State Photoconversion in Dianthrylnaphthalene‐Based Molecular Solar Thermal Systems

open access: yesAngewandte Chemie, EarlyView.
Three dianthrylnaphthalenes were synthesized and investigated for molecular solar thermal (MOST) energy storage. Naphthyl‐based bridging units preorganize the two anthracene moieties face‐to‐face, leading to improved photoisomerization quantum yield (QY) and unlocked bidirectional photoswitching in the solid state compared to previously reported ortho ...
Nicolò Baggi   +10 more
wiley   +2 more sources

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