Results 121 to 130 of about 1,944,890 (372)

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles

Journal of Extracellular Vesicles, 2014
Secreted membrane-enclosed vesicles, collectively called extracellular vesicles (EVs), which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and other EV subsets, encompass a very rapidly growing scientific field in biology ...
J. Lötvall, A. Hill, F. Hochberg, E. Buzás, D. Di Vizio, C. Gardiner, Y. Gho, I. Kurochkin, S. Mathivanan, P. Quesenberry, S. Sahoo, H. Tahara, M. Wauben, K. Witwer, C. Théry   +14 more
semanticscholar   +1 more source

Overview of Protocols for Studying Extracellular RNA and Extracellular Vesicles [PDF]

, 2018
Understanding the role of extracellular RNA (exRNA) has emerged as an exciting avenue for biomarker, therapeutic, as well as basic cell-cell communication applications and discoveries. Multiple protocols, kits, and procedures have been developed in the last decade to allow fractionation as well as isolation of subpopulations of macromolecules of ...
Sabrina Roy, Sabrina Roy, Roger P. Alexander, Leonora Balaj, Julia L. Small   +4 more
openaire   +3 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Evidence for frequency-dependent extracellular impedance from the transfer function between extracellular and intracellular potentials [PDF]

arXiv, 2009
We examine the properties of the transfer function F_T = V_m / V_{LFP} between the intracellular membrane potential (V_m) and the local field potential (V_{LFP}) in cerebral cortex. We first show theoretically that, in the subthreshold regime, the frequency dependence of the extracellular medium and that of the membrane potential have a clear incidence
arxiv  

Extracellular regulation of metalloproteinases

Matrix Biology, 2015
Matrix metalloproteinases (MMPs) and adamalysin-like metalloproteinase with thrombospondin motifs (ADAMTSs) belong to the metzincin superfamily of metalloproteinases and they play key roles in extracellular matrix catabolism, activation and inactivation of cytokines, chemokines, growth factors, and other proteinases at the cell surface and within the ...
Yamamoto, Kazuhiro, Murphy, Gillian, Troeberg, Linda   +2 more
openaire   +5 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Extracellular Electrophysiological Measurements of Cooperative Signals in Astrocytes Populations

Frontiers in Neural Circuits, 2017
Astrocytes are neuroglial cells that exhibit functional electrical properties sensitive to neuronal activity and capable of modulating neurotransmission.
Ana L. G. Mestre, Ana L. G. Mestre, Pedro M. C. Inácio, Pedro M. C. Inácio, Youssef Elamine, Youssef Elamine, Sanaz Asgarifar, Sanaz Asgarifar, Ana S. Lourenço, Ana S. Lourenço, Maria L. S. Cristiano, Maria L. S. Cristiano, Paulo Aguiar, Paulo Aguiar, Maria C. R. Medeiros, Inês M. Araújo, Inês M. Araújo, João Ventura, Henrique L. Gomes, Henrique L. Gomes   +19 more
doaj   +1 more source

The Extracellular Matrix: Not Just Pretty Fibrils

Science, 2009
The extracellular matrix (ECM) and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases. The ECM has many effects beyond providing structural support.
R. Hynes
semanticscholar   +1 more source

THE EXTRACELLULAR RELEASE OF ECHINOCHROME [PDF]

Journal of General Physiology, 1946
A study was made of the diffusion of the red pigment echinochrome from the eggs of the sea urchin, Arbacia punctulata, into sea water. Unfertilized eggs retained their pigment, over periods of hours. Outward diffusion of pigment from unfertilized eggs normally is entirely negligible, or does not occur at all.
openaire   +4 more sources

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source