Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos +17 more
wiley +1 more source
The flavonoid rutin protects against imidacloprid-induced osmotic and electric disruptions in Africanized honey bees. [PDF]
PLoS OneHernández JP, Mesa F, Riveros AJ.
europepmc +1 more source
THE EXTRACELLULAR AND INTRACELLULAR WATER IN BONE AND CARTILAGE
, 1938 Vivian Iob, W.W. Swanson
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Influence of Expansion of Extracellular Volume on Tubular Reabsorption of Sodium Independent of Changes in Glomerular Filtration Rate and Aldosterone Activity * [PDF]
, 1964 Floyd C. Rector +3 more
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Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
Reassessment of extracellular and intracellular activity of macrolides, rifampicin, and doxycycline against <i>Rhodococcus equi</i> based on bacterial counts and microscopy. [PDF]
Microbiol SpectrHuguet A-S +4 more
europepmc +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
Survey of Microorganisms for the Production of Extracellular Phytase [PDF]
, 1968 T. R. Shieh, J. H. Ware
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Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan +12 more
wiley +1 more source
Intracellular Acid-Base Regulation. II. The Interaction between CO2 Tension and Extracellular Bicarbonate in the Determination of Muscle Cell pH * [PDF]
, 1965 Sheldon Adler +2 more
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