Results 81 to 90 of about 1,944,890 (372)
Circulating Small RNA Profiling of Patients with Alveolar and Cystic Echinococcosis
Biology, 2023 Alveolar (AE) and cystic (CE) echinococcosis are two parasitic diseases caused by the tapeworms Echinococcus multilocularis and E. granulosus sensu lato (s. l.), respectively.
Marcela A. Cucher +7 more
doaj +1 more source
Biology of the Extracellular Proteasome
Biomolecules, 2022 Proteasomes are traditionally considered intracellular complexes that play a critical role in maintaining proteostasis by degrading short-lived regulatory proteins and removing damaged proteins. Remarkably, in addition to these well-studied intracellular roles, accumulating data indicate that proteasomes are also present in extracellular body fluids ...
Gili Ben-Nissan +3 more
openaire +3 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Sampling the intramyocellular triglycerides from skeletal muscle
Journal of Lipid Research, 2001 To determine the extent and microanatomical distribution of extramyocellular adipocytes associated with skeletal muscle, histological, biochemical, nuclear magnetic resonance proton spectroscopic and microcomputed tomography techniques were employed to ...
Zengkui Guo +2 more
doaj
Immunity, Inflammation and Disease, 2021 Background: Migration, production of reactive oxygen species (ROS), release of myeloperoxidase (MPO), and NETosis are functional immunological reactions of elementary importance for polymorphonuclear neutrophils (PMN).
Richard F. Kraus +2 more
doaj +1 more source
Extracellular Matrix of Echinoderms
Marine Drugs, 2023 This review considers available data on the composition of the extracellular matrix (ECM) in echinoderms. The connective tissue in these animals has a rather complex organization. It includes a wide range of structural ECM proteins, as well as various proteases and their inhibitors. Members of almost all major groups of collagens, various glycoproteins,
Igor Yu. Dolmatov +1 more
openaire +3 more sources
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Extracellular RNA in oncogenesis, metastasis and drug resistance
RNA BiologyExtracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological state ...
Hannah Nelson +8 more
doaj +1 more source
Control of Intracellular Calcium Signaling as a Neuroprotective Strategy
Molecules, 2010 Both acute and chronic degenerative diseases of the nervous system reduce the viability and function of neurons through changes in intracellular calcium signaling.
R. Scott Duncan +5 more
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Frontiers in Systems Neuroscience, 2020 Deciphering useful information from electrophysiological data recorded from the brain, in-vivo or in-vitro, is dependent on the capability to analyse spike patterns efficiently and accurately.
Rakesh Veerabhadrappa +3 more
doaj +1 more source