Results 81 to 90 of about 2,493,789 (332)

Modeling cell movement in anisotropic and heterogeneous network tissues [PDF]

open access: yes, 2007
Cell motion and interaction with the extracellular matrix is studied deriving a kinetic model and considering its diffusive limit. The model takes into account of chemotactic and haptotactic effects, and obtains friction as a result of the interactions ...
Chauviere, A.   +2 more
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Extracellular Matrix of Echinoderms

open access: yesMarine Drugs, 2023
This review considers available data on the composition of the extracellular matrix (ECM) in echinoderms. The connective tissue in these animals has a rather complex organization. It includes a wide range of structural ECM proteins, as well as various proteases and their inhibitors. Members of almost all major groups of collagens, various glycoproteins,
Igor Yu. Dolmatov   +1 more
openaire   +3 more sources

Immune Modulation by Human Secreted RNases at the Extracellular Space

open access: yesFrontiers in Immunology, 2018
The ribonuclease A superfamily is a vertebrate-specific family of proteins that encompasses eight functional members in humans. The proteins are secreted by diverse innate immune cells, from blood cells to epithelial cells and their levels in our body ...
Lu Lu   +3 more
doaj   +1 more source

ATP is an essential autocrine factor for pancreatic β‐cell signaling and insulin secretion

open access: yesPhysiological Reports, 2022
ATP has been previously identified as an autocrine signaling factor that is co‐released with insulin to modulate and propagate β‐cell activity within islets of Langerhans.
Sebastian Hauke   +4 more
doaj   +1 more source

Circulating Small RNA Profiling of Patients with Alveolar and Cystic Echinococcosis

open access: yesBiology, 2023
Alveolar (AE) and cystic (CE) echinococcosis are two parasitic diseases caused by the tapeworms Echinococcus multilocularis and E. granulosus sensu lato (s. l.), respectively.
Marcela A. Cucher   +7 more
doaj   +1 more source

Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells [PDF]

open access: yes, 2016
Considerable progress has been made in recent years toward elucidating the correlation among nanoscale topography, mechanical properties, and biological behavior of cardiac valve substitutes.
Aguiari, Paola   +11 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Biology of the Extracellular Proteasome

open access: yesBiomolecules, 2022
Proteasomes are traditionally considered intracellular complexes that play a critical role in maintaining proteostasis by degrading short-lived regulatory proteins and removing damaged proteins. Remarkably, in addition to these well-studied intracellular roles, accumulating data indicate that proteasomes are also present in extracellular body fluids ...
Gili Ben-Nissan   +3 more
openaire   +3 more sources

Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings

open access: yesFrontiers in Oncology, 2018
PurposeTo examine the usefulness of rich diffusion protocols with high b-values and varying diffusion time for probing microstructure in bone metastases.
Colleen Bailey   +11 more
doaj   +1 more source

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